A combined pulse generating circuit and method applied to pulsed electric field ablation technology

Abstract

The present invention relates to a combined pulse generating circuit applied to pulsed electric field ablation technology in the field of high-voltage pulse application. The combined pulse generating circuit includes multiple full-bridge topology generating circuits, and the full-bridge topology generating circuit includes capacitors and multiple switches. Among them, the multiple Two switches are connected in series to form a switch branch, multiple switch branches and capacitors are connected in parallel, and the switches of multiple full-bridge topology generating circuits form a full-bridge topology; the output of the combined pulse generating circuit includes at least one or more of the following pulses Combination: positive pulse, zero pulse, negative pulse. The beneficial effect is that under the premise of realizing the same function, the circuit voltage control is simpler, the cost is reduced, and the difficulty of circuit design is reduced. The precise control of the high-voltage pulse signal is realized, and the output high-voltage pulse signal is flexible and adjustable, which can meet various needs of clinical application and ensure the safety of clinical application.

Description

technical field [0001] The invention relates to the application field of high-voltage pulses, in particular to a combined pulse generating circuit and method applied to pulse electric field ablation technology. Background technique [0002] Existing treatments for tachyarrhythmias often use thermal ablation techniques such as radiofrequency and freezing. Among them, radio frequency technology can generate a fixed frequency sine wave. The generated radiofrequency energy acts on the lesion to be treated through the radiofrequency catheter or radiofrequency electrode, so that it can achieve the effect of blocking or conditioning, and then achieve the therapeutic effect. Cryoablation absorbs heat through the evaporation process of the liquid refrigerant in the cryoballoon, causing the temperature around the ablation target to drop suddenly. Through low temperature, the tissue cells in the lesion area are damaged or killed, so as to achieve the purpose of treatment. These abla...

AI Technical Summary

Problems solved by technology

[0005] However, when pulsed electric field ablation, a non-thermal effect ablation technology, is applied to treatment, new problems are faced, for example, how to realize the precise control of high-voltage pulse signals, and how to make the output high-voltage pulse signals flexible and adjustable to meet clinical applications. Various needs, and can guarantee the safety of clinical application

If the above problems cannot be solved, it will greatly affect the further clinical application of pulsed electric field ablation technology.

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