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No-clean and alcohol-free hand disinfectant and preparation method thereof

A disinfectant and hand-use technology, which is applied in the field of disposable hand-use disinfectant without alcohol and its preparation, can solve the problems of poor anti-virus effect, skin irritation, pungent smell, etc., achieve fast sterilization speed and prolong service life , soothing effect

Inactive Publication Date: 2020-06-26
山东名德医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Hand-free sanitizers are popular because of their ease of use, but most of the hand-free sanitizers in the prior art contain higher levels of alcohol solvents, which have a strong pungent smell and irritate the skin, and also have the ability to kill viruses in a short time The defect of poor effect

Method used

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  • No-clean and alcohol-free hand disinfectant and preparation method thereof
  • No-clean and alcohol-free hand disinfectant and preparation method thereof
  • No-clean and alcohol-free hand disinfectant and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0029] A disposable alcohol-free hand sanitizer, which is composed of the following raw materials according to the mass fraction: polyhexamethylene biguanide 0.18%, dodecyl dimethyl benzyl ammonium chloride 0.27%, glycerol 0.3 %, 0.1% lemon essential oil, 0.1% lemon yellow pigment, and the balance is purified water. According to mass fraction, the active ingredient content of the above-mentioned polyhexamethylene biguanide is 19.0%, and dodecyl dimethyl benzyl ammonium chloride The active ingredient content is 80.0%, the glycerin active ingredient content is 99.5%, the above-mentioned lemon essential oil active ingredient content is 99.0%, the lemon yellow pigment active ingredient content is 99.0%, and the above-mentioned purified water is medical grade purified water.

Embodiment 2

[0031] A disposable alcohol-free hand sanitizer, which is composed of the following raw materials according to the mass fraction: polyhexamethylene biguanide 0.22%, dodecyl dimethyl benzyl ammonium chloride 0.33%, glycerol 1.0 %, 0.5% lemon essential oil, 0.6% lemon yellow pigment, and the balance is purified water. In terms of mass fraction, the active ingredient content of the above-mentioned polyhexamethylene biguanide is 20.0%, the active ingredient content of dodecyldimethylbenzyl ammonium chloride is 85.0%, the active ingredient content of glycerin is 99.8%, and the above-mentioned lemon The active ingredient content of the essential oil is 99.5%, the effective ingredient content of lemon yellow pigment is 99.5%, and the above-mentioned purified water is medical-grade purified water.

Embodiment 3

[0033] A disposable alcohol-free hand sanitizer, made of the following components by weight: 0.20% polyhexamethylene biguanide, 0.2% dodecyldimethylbenzyl ammonium chloride, glycerol 0.6%, lemon essential oil 0.3%, lemon yellow pigment 0.3%, and the balance is purified water. In terms of mass fraction, the active ingredient content of the above-mentioned polyhexamethylene biguanide is 21.0%, the active ingredient content of dodecyldimethylbenzyl ammonium chloride is 90.0%, the active ingredient content of glycerin is 99.8%, and the above-mentioned lemon The active ingredient content of the essential oil is 99.8%, the effective ingredient content of lemon yellow pigment is 99.8%, and the above-mentioned purified water is medical-grade purified water.

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Abstract

The invention discloses a no-clean and alcohol-free hand disinfectant. The no-clean and alcohol-free hand disinfectant comprises the following raw materials in percentage by mass: 0.18-0.22% of polyhexamethylene biguanidine hydrochloride (PHMB), 0.27-0.33% of dodecyl dimethyl benzyl ammonium chloride, 0.3-1.0% of glycerol, 0.1-0.5% of lemon essential oil, 0.1-0.6% of lemon essential oil, and the balance purified water. The no-clean and alcohol-free hand disinfectant prepared by the invention adopts a complex formula of biguanide and quaternary ammonium salt, has a wide bacteriocidal spectrum,is quick in sterilization, can ensure the sterilization effect, adopts an alcohol-free formula, and has low irritation.

Description

technical field [0001] The invention belongs to the technical field of disinfectants, in particular to a no-cleaning and alcohol-free hand disinfectant and a preparation method thereof. Background technique [0002] With the improvement of medical level, hand hygiene has received more and more attention. A large number of epidemiological studies have shown that nosocomial infections are usually transmitted directly or indirectly through hands, especially medical staff often carry a large number of pathogenic bacteria on their hands, and sometimes even for Super pathogen drug resistant bacteria. Hands are the main medium for the transmission of pathogenic bacteria. Nosocomial infections caused by bacteria transmitted by hands accounted for 30% of all factors. A large number of literature studies have shown that hand washing is the best way to reduce hospital-acquired infections economically and effectively. [0003] Hand-free sanitizers are popular because of their ease of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/92A61K8/84A61K8/41A61K8/34A61Q17/00A61Q19/10
CPCA61K8/345A61K8/416A61K8/84A61K8/922A61K2800/72A61Q17/005A61Q19/10
Inventor 尤翠红张艳玲
Owner 山东名德医疗科技有限公司
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