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Traditional Chinese medicinal composition with function of improving bone health and preparation method thereof

A technology of composition and traditional Chinese medicine, applied in the directions of drug combination, bone disease, pharmaceutical formula, etc., can solve problems such as side effects, and achieve the effect of stable drug effect, good therapeutic effect and remarkable effect

Inactive Publication Date: 2020-06-19
YANTAI NEW ERA HEALTH IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the therapeutic effect of western medicine is good, long-term use will produce some side effects

Method used

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  • Traditional Chinese medicinal composition with function of improving bone health and preparation method thereof
  • Traditional Chinese medicinal composition with function of improving bone health and preparation method thereof
  • Traditional Chinese medicinal composition with function of improving bone health and preparation method thereof

Examples

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Effect test

Embodiment 1

[0046] A traditional Chinese medicine composition for improving bone health. The raw materials include 20 parts by weight of pine pollen, 15 parts of phoenix leaves, 15 parts of pine knots and 10 parts of macaque pear root.

[0047] The preparation method of above-mentioned Chinese medicine composition is as follows:

[0048] (1) Crushing of raw materials: the pine pollen was broken for 30 minutes by airflow pulverization to obtain broken pine pollen; the sycamore leaves, pine knots, and macaque pear roots were pulverized and sieved to obtain 60-mesh powder; according to the formula The amount is weighed to form a mixed raw material powder;

[0049] (2) Leaching: put the mixed raw material powder and the ethanol of concentration 80% into the extraction tank, extract for 0.5h, and filter to obtain the ethanol extract; keep stirring during the extraction process; the mass ratio of the mixed raw material powder and ethanol is 1: 10;

[0050] (3) Extraction: Put the ethanol extr...

Embodiment 2

[0054] A traditional Chinese medicine composition for improving bone health. The raw materials include 25 parts of pine pollen, 20 parts of phoenix leaves, 20 parts of pine knots and 20 parts of macaque pear root in parts by weight.

[0055] The preparation method of above-mentioned Chinese medicine composition is as follows:

[0056] (1) Crushing of raw materials: the pine pollen was broken for 25 minutes by airflow pulverization to obtain the broken pine pollen; the sycamore leaves, pine knots, and macaque pear roots were pulverized and sieved to obtain 80-mesh powder; according to the formula The amount is weighed to form a mixed raw material powder;

[0057] (2) Extraction: Put the mixed raw material powder and 90% ethanol into the extraction tank, extract for 1 hour, and filter to obtain the ethanol extract; keep stirring during the extraction process; the mass ratio of the mixed raw material powder to ethanol is 1:8 ;

[0058] (3) Extraction: Put the ethanol extract into...

Embodiment 3

[0062] A traditional Chinese medicine composition for improving bone health. The raw materials include 30 parts of pine pollen, 30 parts of phoenix leaves, 30 parts of pine knots and 30 parts of macaque pear root in parts by weight.

[0063] The preparation method of above-mentioned Chinese medicine composition is as follows:

[0064] (1) Crushing of raw materials: the pine pollen was broken for 25 minutes by airflow pulverization to obtain the broken pine pollen; the sycamore leaves, pine knots, and macaque pear roots were pulverized and sieved to obtain 100-mesh powder; according to the formula The amount is weighed to form a mixed raw material powder;

[0065] (2) Lixiviation: put mixed raw material powder and the ethanol of concentration 95% into extraction tank, leaching 1.5h, filter and obtain ethanol extract; Continuous stirring in the leaching process; The mass ratio of mixed raw material powder and ethanol is 1: 5;

[0066] (3) Extraction: Put the ethanol extract in...

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Abstract

The invention discloses a traditional Chinese medicinal composition with a function of improving the bone health. The traditional Chinese medicinal composition is prepared from the following raw materials in parts by weight: 20-30 parts of pollen pini, 15-30 parts of phoenix tree leaves, 15-30 parts of loose knots and 10-30 parts of bower actinidia roots. The invention further discloses a preparation method of the traditional Chinese medicinal composition. The preparation method comprises the following steps: (1) grinding raw materials, namely grinding the raw materials, and mixing the raw materials to obtain mixed raw material powder; (2) performing digestion, namely performing digestion on the mixed raw material powder obtained in the step (1) with alcohol to obtain a leaching liquid; (3) performing extraction, namely performing supercritical CO2 extraction on the leaching liquid obtained in the step (2) to obtain an extract crude product; and (4) performing purification, namely purifying the extract crude product obtained in the step (3) with high-speed countercurrent chromatography. The traditional Chinese medicinal composition has a relatively good treatment effect on improving the bone health and has a remarkable effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for improving bone health and a preparation method thereof. Background technique [0002] Bone health is a "big concept", referring to the health of the entire skeletal system, including bones, cartilage, joints, tendons, ligaments, etc. In China and other parts of the world, as the degree of aging increases, the most common bone health problems are osteoporosis and osteoarthritis. [0003] Osteoporosis is a systemic bone disease. Its pathology is the decrease of bone mass and the destruction of bone microstructure, which is manifested by the increase of bone fragility, so the risk of fracture is greatly increased, even in the case of minor trauma or no trauma It is also prone to fractures. The risk of osteoporotic fracture was 39.7% in women and 13.1% in men. It is estimated that from 2020 to 2050, the number o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P19/08A61P19/10A61K36/15
CPCA61K36/15A61K36/185A61K2236/333A61K2236/37A61P19/08A61P19/10A61K2300/00
Inventor 杨长军马云徐宏楠刘其耸王桐
Owner YANTAI NEW ERA HEALTH IND
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