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Antibacterial foam dressing and preparation method thereof

A foam and foam stabilizer technology, which is applied in the fields of medical science, bandages, absorbent pads, etc., can solve the problems of difficult release and poisoning of metal particles, and achieve the effects of saving medical expenses, simple preparation method and large contact surface area.

Active Publication Date: 2020-04-14
ROOSIN MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to prepare a metal material with good bacteriostatic effect and durability, which is closely combined with the foam material as an antibacterial component, so that the metal particles are not easy to be released from the foam dressing, so as to avoid the accumulation of antibacterial metal particles in the human body And antibacterial foam dressings that are toxic to human tissues and organs

Method used

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  • Antibacterial foam dressing and preparation method thereof
  • Antibacterial foam dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] (1) Disperse 0.05g of copper powder with a particle size of 0.5μm in 100g of Bayhydur 305 and stir evenly to obtain component A;

[0041] (2) Water, 1,4 butanediol, K2800, B8110, 33LV mixed evenly to obtain component B;

[0042] (3) 100g A component and 100g B component are mixed with 6000rpm high-shear stirring speed in a dynamic mixer, and react to obtain C component;

[0043] (4) Quickly extrude component C onto the release paper to form a foam, adjust the thickness of the foam to 10mm, and then dry it at 105°C for 3 minutes to obtain an antibacterial foam dressing. The foaming density of the antibacterial foam dressing is 120kg / m 3 , The diameter of the open cell is 0.8mm.

Embodiment 2

[0045] (1) Disperse 3 g of zinc-copper alloy powder with a particle size of 10 μm and a copper content of 80% in 100 g of Bayhydur BL5140, and stir evenly to obtain component A;

[0046] (2) Water, ethylene glycol, K757, DC6070, Mix A-1 evenly to obtain component B;

[0047] (3) Mix 50g of component A with 100g of component B in a dynamic mixer at a high-shear stirring speed of 6000rpm, and react to obtain component C;

[0048] (4) Quickly extrude component C onto the release paper to form a foam, adjust the thickness of the foam to 10mm, and then dry it at 105°C for 5 minutes to obtain an antibacterial foam dressing. The foaming density of the antibacterial foam dressing is 50kg / m 3 , The diameter of the open cell is 3mm.

Embodiment 3

[0050] (2) Disperse 5g of zinc powder with a particle size of 60μm in 100g of WanCURE TP611 and stir evenly to obtain component A;

[0051] (2) Water, 1,6 hexanediol, Y-1900, PM-300, Mix AN-33 evenly to obtain component B;

[0052] (3) 100g A component and 50g B component are mixed with 6000rpm high-shear stirring speed in a dynamic mixer, and react to obtain C component;

[0053] (4) Quickly extrude component C onto the release paper to form a foam, adjust the thickness of the foam to 10mm, and then dry it at 105°C for 10 minutes to obtain an antibacterial foam dressing. The foaming density of the antibacterial foam dressing is 300kg / m 3 , The diameter of the open cell is 0.05mm.

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Abstract

The invention relates to the field of medical dressings, in particular to an antibacterial foam dressing and a preparation method thereof. The invention aims to prepare the antibacterial foam dressingwhich is good in antibacterial effect and durable in use, a metal material serving as an antibacterial component is tightly combined with a foam material, metal particles are not easily released fromthe foam dressing, and antibacterial metal particles can be prevented from accumulating in the human body and generating toxic action on human body tissues and organs. According to the antibacterialfoam dressing provided by the invention, antibacterial metal powder is added before foaming of the polyurethane material, so that the antibacterial metal powder is embedded into the polyurethane foaming material, tight combination of the two substances can more effectively prevent the antibacterial metal powder from being released from the polyurethane foaming material and entering the human bodyblood, thus preventing the metal particles from accumulating in the human body and generating toxic action on human body tissues and organs. The antibacterial foam dressing prepared by the method provided by the invention has simple preparation process, and has better antibacterial effect and antibacterial durability.

Description

technical field [0001] The invention relates to the field of medical dressings, in particular to an antibacterial foam dressing and a preparation method thereof. Background technique [0002] With the development and improvement of medical technology, there are more and more types of functional dressings related to wound care. And dressings with antibacterial properties have been paid more and more attention by people, and have been researched and developed accordingly. Compared with traditional dressings, it has the effect of preventing wound infection or controlling wound infection. The types of antibacterial dressings on the market include foam or sponge dressings, alginate, chitosan, hydrogel, etc. The antibacterial ingredients in dressings mainly include various organic or inorganic chemical disinfectants, natural Antibacterial animal and plant extracts, various soluble metal ion solutions, metal complexes, nanoscale metal inclusion materials, etc. The preparation pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/18A61L15/26A61L15/42A61L15/44A61L15/46
CPCA61L15/26A61L15/18A61L15/44A61L15/46A61L15/425A61L2300/102A61L2300/404C08L75/04
Inventor 陈达永楮加冕褚省吾陈丽琦
Owner ROOSIN MEDICAL CO LTD
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