Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A recyclable liquid bead that can realize light-responsive directional movement and release antibacterial drugs in an aqueous medium and preparation method

A technology of directional movement and aqueous media, which is applied in botany equipment and methods, animal repellents, chemicals for biological control, etc., and can solve the problems of unclear functionality, complicated preparation process, unstable response, etc. problem, to achieve the effect of simple preparation process, favorable diffusion, and improvement of photoresponse displacement

Active Publication Date: 2022-05-03
刘红枚
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it has a series of disadvantages, such as complex preparation process, slow movement speed, unstable response and unclear functionality, etc.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A recyclable liquid bead that can realize light-responsive directional movement and release antibacterial drugs in an aqueous medium and preparation method
  • A recyclable liquid bead that can realize light-responsive directional movement and release antibacterial drugs in an aqueous medium and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Firstly, spiropyran and chlorobenzene with a molar ratio of 1:2 were dissolved in tetrahydrofuran, and reacted for 0.5 hours at a pH of 8 and a temperature of 60° C. to obtain product 1. Propionyl chloride and anhydrous ferric chloride with a molar ratio of 1:1 were slowly dissolved in ether to prepare a solution with a mass percentage of 5 wt%, which was used as an acylation solution for later use. The acylation solution was slowly added dropwise to the above product 1, stirred rapidly to make it fully mixed and reacted at 10° C. for 0.5 hour to obtain product 2. Wherein the molar ratio of propionyl chloride in the acylation solution to product 1 is 1:0.5. The product 2 and N,N-dimethylalkylamine with a molar ratio of 1:0.8 were used for quaternization reaction to obtain the product 3. Then the above product 3 is subjected to hydrogenation under Pd / C catalysis to obtain the product helical pyranyl quaternary ammonium salt and its derivatives.

[0029] Mix the helical...

Embodiment 2

[0035] First, spiropyran and chlorobenzene with a molar ratio of 1:3 were dissolved in tetrahydrofuran, and reacted for 2 hours at a pH of 8 and a temperature of 55° C. to obtain product 1. Propionyl chloride and anhydrous ferric chloride with a molar ratio of 1:3 were slowly dissolved in ether to prepare a solution with a mass percentage of 15 wt%, which was used as an acylation solution for later use. The acylation solution was slowly added dropwise to the above-mentioned product 1, stirred rapidly to make it fully mixed and reacted at 10° C. for 1 hour to obtain product 2. Wherein the molar ratio of propionyl chloride in the acylation solution to product 1 is 1:1. Take product 2 and N,N-dimethylalkylamine at a molar ratio of 1:1 for quaternization reaction to obtain product 3. Then the above product 3 is subjected to hydrogenation under Pd / C catalysis to obtain the product helical pyranyl quaternary ammonium salt and its derivatives.

[0036] The helical pyranyl quaternar...

Embodiment 3

[0042]First, spiropyran and chlorobenzene with a molar ratio of 1:5 were dissolved in dichloromethane, and reacted for 1 hour at a pH of 9 and a temperature of 35°C to obtain product 1. Propionyl chloride and anhydrous ferric chloride with a molar ratio of 1:3 were slowly dissolved in ether to prepare a solution with a mass percentage of 25 wt%, which was used as an acylation solution for later use. The acylation solution was slowly added dropwise to the above product 1, stirred rapidly to make it fully mixed and reacted at 15°C for 2 hours to obtain product 2. Wherein the molar ratio of propionyl chloride in the acylation solution to product 1 is 1:1.5. Take product 2 and N,N-dimethylalkylamine at a molar ratio of 1:2 for quaternization reaction to obtain product 3. Then the above product 3 is subjected to hydrogenation under Pd / C catalysis to obtain the product helical pyranyl quaternary ammonium salt and its derivatives.

[0043] Mix the helical pyranyl quaternary ammoniu...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
diameteraaaaaaaaaa
diameteraaaaaaaaaa
Login to View More

Abstract

The invention relates to a recyclable liquid bead capable of realizing light-responsive directional movement and releasing antibacterial drugs in an aqueous medium and a preparation method thereof. The liquid bead system of the present invention is prepared from a helical pyranyl quaternary ammonium salt and its derivatives, an acidic substance, an auxiliary enhancer and an organic solvent, and the preparation method is that the helical pyranyl quaternary ammonium salt and its derivative After mixing uniformly, acidic substances and auxiliary agents, they are added to organic solvents to avoid light to disperse, and then injected into liquid medium through a micro-injection pump to form liquid beads. The whole preparation process is easy to operate and the conditions are mild, and the types and concentrations of raw materials can be adjusted according to the application conditions to prepare corresponding liquid beads. The liquid beads prepared by the invention can realize forward or reverse directional movement under the irradiation of a specific light source and have the characteristic of releasing antibacterial drugs during the directional movement. Moreover, the liquid beads can be recovered after drug release, so as to avoid the pollution of the organic relative water phase medium system after the liquid beads are destabilized.

Description

technical field [0001] The invention belongs to the technical field of intelligent responsive materials, and in particular relates to a recyclable liquid bead capable of realizing light-responsive directional movement and releasing antibacterial drugs in an aqueous medium and a preparation method thereof. Background technique [0002] Aqueous media are widely used in the fields of instruments, landscape facilities and medical devices. Long-term use is susceptible to microbial infection, resulting in a decline in the use effect, and endangering the health of users. Because the water phase medium is not suitable for stirring, Gu mostly adopts traditional disinfection methods, relying on adding a large amount of disinfectant and dissolving and diffusing the disinfectant to kill harmful microorganisms. In this way, not only the large amount of disinfectant used will cause the risk of local concentration being too high, but also the efficiency cannot be guaranteed. In addition,...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A01N25/02A01N43/16A01P1/00A01P3/00C07D311/96
CPCA01N25/02A01N43/16C07D311/96
Inventor 王泽锋吴香梅王玲楠汪亮亮张春牛罗梦婷兰巧巧
Owner 刘红枚
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com