Pharmaceutical composition for use in treatment or prevention of vitamin deficiency and mineral deficiency in patients who have been subjected to gastric sleeve surgery

A technology of vitamin deficiency and composition, applied in the field of vitamin and mineral deficiency in patients, pharmaceutical composition, deficiency and mineral deficiency, can solve problems such as lowering, vitamin and mineral deficiency

Pending Publication Date: 2020-03-31
AMS ADVANCED MEDICAL SUPPLEMENTS BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is not known which vitamins and minerals (doses) can be safely given to gastric sleeve patients such that these patients are at reduced risk ...

Method used

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  • Pharmaceutical composition for use in treatment or prevention of vitamin deficiency and mineral deficiency in patients who have been subjected to gastric sleeve surgery
  • Pharmaceutical composition for use in treatment or prevention of vitamin deficiency and mineral deficiency in patients who have been subjected to gastric sleeve surgery
  • Pharmaceutical composition for use in treatment or prevention of vitamin deficiency and mineral deficiency in patients who have been subjected to gastric sleeve surgery

Examples

Experimental program
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Effect test

Embodiment

[0247] Double-blind comparison of two pharmaceutical compositions according to the invention ('GS-B') with a standard multivitamin supplement ('R') randomized study

[0248] A double-blind, randomized, six-month study was conducted comparing the multivitamin / multimineral composition 'GS-B' of the present invention with approximately 100% of the Recommended Daily Allowance (RDA) of iron, A standard multivitamin supplement ('R') of vitamin B12 and folic acid was compared (see Tables 1 and 2 for details). GS-B contains vitamin B12 at a level of 4000% RDA, iron at a level of 200% RDA and folic acid at a level of 250% RDA per capsule.

[0249] patient

[0250]A total of 98 patients scheduled for gastric sleeve surgery were randomly assigned to postoperative multivitamin / multimineral supplementation for a period of six months. All patients met the criteria for bariatric surgery according to the NIH Bariatric Surgery Consensus Development Conference Group. Patients were rando...

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Abstract

The invention relates to a pharmaceutical composition comprising vitamin B12 and iron for use in the treatment or prevention of vitamin and mineral deficiencies in patients which have been subjected to gastric sleeve surgery. The present invention further relates to the pharmaceutical composition as such.

Description

[0001] invention technical field [0002] The present invention relates to a pharmaceutical composition for the treatment or prevention of vitamin and mineral deficiencies in patients who have undergone gastric sleeve surgery. The present invention therefore also relates to pharmaceutical compositions. Furthermore, the present invention relates to methods for treating or preventing vitamin and mineral deficiencies in patients who have undergone gastric sleeve surgery. [0003] Background of the invention [0004] Bariatric surgery was first introduced in the United States in the 1960s as a treatment for morbid obesity. Over the past decade, the number of weight loss programs has increased rapidly. This increase is largely due to an increase in the number of people who are morbidly obese. Patients with morbid obesity are at increased risk of many different diseases, such as type II diabetes, coronary heart disease, hyperlipidemia, hypertension, sleep apnea, osteoarthritis, se...

Claims

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Application Information

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IPC IPC(8): A61K31/714A61K33/26A61K45/00A61P3/02
CPCA61K31/714A61K33/26A61P3/02A61K2300/00
Inventor 舒尔德·阿里·皮尔特·范伯克尔
Owner AMS ADVANCED MEDICAL SUPPLEMENTS BV
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