Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Composite nano material and preparation method and application thereof

A technology of composite nanomaterials and supramolecular compounds, which is applied in the field of nanomaterials to achieve good biocompatibility, low cytotoxicity and remarkable effects

Active Publication Date: 2019-10-22
YUNNAN UNIV
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This new type of carbon material called CNS (Conductive Polymer Network) was discovered during research for its potential use in medicine applications such as drug delivery systems. It's effective at preventing cancer growth without harmful side effects from chemotherapeutic agents used against other types of tumors that are known to cause damage. Additionally, it could help improve blood flow through living tissues when placed near certain parts of our body where there may develop small holes due to disease conditions like arteriosclerosis.

Problems solved by technology

The technical problem addressed in this patented text relates to finding ways to prevent or reduce excessive cellular damage caused by programmed cell deaths due to lack of proper mechanisms involved in their formation. This could lead to diseases like cancer if it occurs naturally over time without any treatment being done properly.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composite nano material and preparation method and application thereof
  • Composite nano material and preparation method and application thereof
  • Composite nano material and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The preparation method of BPNS@cPA6 composite nanomaterials, the specific steps are as follows:

[0035] (1) Black phosphorus crystals (100 mg) were dispersed in anaerobic water (50 mL), sonicated in an ice bath for 10 h, and centrifuged at 1500 rpm for 10 minutes to obtain a suspension of BPNS to remove unstripped black phosphorus crystals, and then Centrifuge at 7000rpm for 15 minutes to obtain the BPNS precipitate, so as to shorten the time required for subsequent freeze-drying, and finally freeze-dry to obtain powder. The whole process is carried out in a dark environment;

[0036] (2) Synthesize cPA6 according to the report in the literature "A cationic water-soluble pillar[5]arene: synthesis and host–guest complexation with sodium 1-octanesulfonate", the specific steps are as follows:

[0037] Step 1, carbon tetrabromide (39.8g, 120mmol) was slowly added into 250mL of anhydrous hydroquinone bis(2-hydroxyethyl) ether (10.0g, 50.4mmol) and triphenylphosphine (31.5g,...

Embodiment 2

[0049] The preparation method of BPNS@cPA6 composite nanomaterials, the specific steps are as follows:

[0050] (1) Black phosphorus crystals (100 mg) were dispersed in anaerobic water (50 mL), sonicated in an ice bath for 6 h, and then centrifuged at 2000 rpm for 10 minutes to obtain a suspension of BPNS to remove unstripped black phosphorus crystals, Then centrifuge at 10,000rpm for 15 minutes to obtain the BPNS precipitate to shorten the time required for subsequent freeze-drying, and finally freeze-dry to obtain powder. The whole process is carried out in a dark environment;

[0051] (2) Prepare cPA6 according to the method of Example 1, disperse the dry powder (10 mg) prepared in step (1) and cPA6 (20 mg) in anaerobic water (10 mL), and ultrasonically in an ice bath for 10 min, After stirring for 6 hours, centrifuge and wash twice at 7000rpm to remove excess cPA6. The whole process was carried out in a dark environment, and BPNS@cPA6 composite nanomaterials were obtained....

Embodiment 3

[0053] A method for preparing BPNS@cPA6 nanometer material, the specific steps are as follows:

[0054] (1) Black phosphorus crystals (100mg) were dispersed in anaerobic water (50mL), sonicated in an ice bath for 12h, and then centrifuged at 500rpm for 10 minutes to obtain a suspension of BPNS to remove unstripped black phosphorus crystals, Then centrifuge at 12000rpm for 15 minutes to obtain the BPNS precipitate to shorten the time required for subsequent freeze-drying, and finally freeze-dry to obtain powder. The whole process is carried out in a dark environment;

[0055] (2) Prepare cPA6 according to the method of Example 1, disperse the dry powder (20 mg) prepared in step (1) and cPA6 (10 mg) in anaerobic water (10 mL), and ultrasonically in an ice bath for 30 min, After stirring for 3 hours, centrifuge washing at 12000rpm for 4 times to remove excess cPA6. The whole process was carried out in a light-proof environment, and BPNS@cPA6 composite nanomaterials were obtained....

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a composite nano material and a preparation method and application thereof. The nano material is composed of a positively charged pillararene supramolecular compound and a black phosphorus nano sheet, and is of a lamellar structure. The nano material can be applied in the preparation of anti-hepatoma drugs. The nano material can enter the hepatoma cell HepG2, and as time goes on, more and more nano materials enter; the nano material has a remarkable inhibition effect on the activity of the cell, and the highest inhibition rate reaches 61.1%; the nano material can promote the occurrence of apoptosis, and is concentration-dependent; the black phosphorus nano sheet has low cytotoxicity, can be degraded by cells after entering the cell, and has good biocompatibility.

Description

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Owner YUNNAN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com