Application of rattlerin in preparing anti-fungal drug sensitizer
An antifungal drug, the technology of saipinin, which is applied in the field of biomedicine, can solve problems such as interference with propagation and growth, and tumor cell death, and achieve the effects of easy acquisition, strong synergy, and reduced clinical dosage
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[0017] The present invention will be described in detail in conjunction with the embodiments, but the implementation of the present invention is not limited thereto.
[0018] The reagents and raw materials used in the present invention are commercially available or can be prepared according to literature methods. For the experimental methods without specific conditions indicated in the following examples, usually follow the conventional conditions or the conditions suggested by the manufacturer. Percentages and parts are by volume unless otherwise indicated.
[0019] 1. Experimental materials
[0020] 1. Drugs and reagents
[0021] Fluconazole was purchased from SigmaAldrich Company in the United States, and chastein was purchased from Tocris Company in the United Kingdom, and were stored at -40°C; dimethyl sulfoxide (DMSO) was purchased from SigmaAldrich Company in the United States; ultra-clean water was purchased from Japan Net Water machine production.
[0022] 2. Stra...
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