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Post-treatment method for nitrocellulose membrane

A technology of nitrocellulose and hydrophilic treatment, which is applied in the field of post-treatment of nitrocellulose membranes, can solve problems such as trajectories and false positive product quality, and achieve fast reading determination, fast off-plate chromatography, and fast The effect of climbing speed

Inactive Publication Date: 2019-07-02
天韧膜科技(苏州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Colloidal gold rapid diagnosis products often have the phenomenon of "trajectory line", that is, sharp thin lines appear on both sides of the color band of the product film, which can easily cause users to misjudge false positives and cause serious product quality problems

Method used

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  • Post-treatment method for nitrocellulose membrane
  • Post-treatment method for nitrocellulose membrane
  • Post-treatment method for nitrocellulose membrane

Examples

Experimental program
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Effect test

Embodiment 1

[0042] The embodiment of the present invention provides a post-treatment method for nitrocellulose membrane, which specifically includes:

[0043] The hydrophilic treatment solution was prepared, and its mass composition was as follows: 0.15% lauryl glucoside, and the remaining components were deionized water, stirred evenly and stood still for use. The hydrophobic nitrocellulose film that has been pre-dried and dedusted is placed in the hydrophilic treatment solution for continuous soaking treatment. The soaking time is 5 minutes, and the film is dried at 50°C. The film test results are shown in Table 2 and Figure 4 In (a), the surface structure of the film is shown in figure 2 ;

Embodiment 2

[0045] The process steps of preparing the film in Example 1 were repeated, the hydrophilic treatment solution was n-hexyl glucoside with a concentration of 0.03%, and the film was dried at 30°C. The film test results are shown in Table 2 and Figure 4 (b) in.

Embodiment 3

[0047] The process steps of preparing the film in Example 1 were repeated, and the hydrophilic treatment solution was a mixture of oligomeric C8-C16 glucosylglycosides, the total concentration of which was 0.20%, and the soaking time was 20 minutes. The film test results are shown in Table 2 and Figure 4 (c) in.

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Abstract

The invention discloses a post-treatment method for a nitrocellulose membrane, comprising the following steps: a hydrophobic nitrocellulose membrane to be treated is fully dried; the dried hydrophobicnitrocellulose membrane is placed into a hydrophilic treatment solution for continuous immersion treatment or is sprayed with the hydrophilic treatment solution; the hydrophilic treatment solution isan alkylpolyglycoside surfactant solution; and the nitrocellulose membrane capable of solving the ''trajectory'' problem after fully drying at 20-75 DEG C. according to the invention, it can be ensured that the detection line of a rapid diagnosis product is clear at the edge and there is no diffusion; the rapid diagnosis product has faster climbing speed; and more importantly, the ''trajectory''problem of the rapid diagnosis product can be greatly reduced or eliminated, and accuracy rate of the rapid diagnosis product is guaranteed.

Description

technical field [0001] In particular, the invention relates to a post-treatment method for nitrocellulose membranes. Background technique [0002] Nitrocellulose, the product of cellulose and nitrate esterification, has good film-forming properties and is one of the earliest polymers used to prepare films in the world. In recent years, due to the polymer characteristics of nitrocellulose itself, its application has gradually shifted from filtration separation to bioanalysis with higher added value, which is mainly due to the non-specific adsorption capacity of nitrocellulose on proteins and other substances. The preparation method of this kind of film can be found in the published Chinese invention patent application with publication number CN103819710A. [0003] On the other hand, the application of rapid diagnostic products requires that the membrane must be hydrophilic, and the hydrophobicity of nitrocellulose itself puts forward requirements for the hydrophilic post-tre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08J9/40C08L1/18
CPCC08J9/40C08J2301/18
Inventor 邢力王平杨启炜姚军
Owner 天韧膜科技(苏州)有限公司
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