Sarcandra injection, preparation method of sarcandra injection, and intravenous administration of sarcandra injection
A technology for injections and sarcomas, applied in the direction of antineoplastic drugs, antipyretics, anti-inflammatory agents, etc., can solve problems such as inconvenient use, muscle necrosis, pain, etc., to avoid inconvenient use and high bioavailability , to avoid the effect of degradation
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Embodiment 1
[0039]Take 1000g of sarcophagus, add 6 times the weight of sarcophagus, boil and decoct 2 times, each time for 2 hours, filter with filter paper, combine the two filtrates, and concentrate each ml of liquid medicine containing 1g of crude drug; add to the concentrated solution Add 0.05% of the weight of the concentrated liquid clarifier B, heat to 70-90 ° C, let stand for 2 hours, then add 0.025% of the weight of the concentrated liquid clarifier A, let stand for 4 hours, centrifuge, and pour the supernatant and concentrated to 3g of crude drug per ml of medicinal liquid; add ethanol under slow stirring, add ethanol to make the alcohol content 75%, refrigerate at 4-8°C for 48 hours, filter with filter paper, recover ethanol from the filtrate, and concentrate to per ml The medicinal solution contains 3g of crude drug, add ethanol to make the alcohol content 85%, refrigerate at 4-8°C for 48 hours, filter with filter paper, recover ethanol from the filtrate, concentrate the filtra...
Embodiment 2
[0041] Get 2000g of sarcophagus, add 8 times the weight of sarcophagus, boil and decoct 2 times, each time for 3 hours, filter with filter paper, combine the two filtrates, and concentrate each ml of medicinal solution containing 1.5g of crude drug; add to the concentrated solution Add 0.04% of the weight of the concentrated solution to the clarifier B, heat to 70-90 ° C, let it stand for 2 hours, then add 0.02% of the weight of the concentrated solution A clarifier, after standing for 4 hours, centrifuge, and the supernatant Pour out and concentrate to 4g of crude drug per ml of liquid medicine; add ethanol under slow stirring, add ethanol to make the alcohol content to 70%, refrigerate at 4-8°C for 48 hours, filter through filter paper, recover ethanol from the filtrate, and concentrate to every The medicinal solution in ml contains 4g of crude drug, add ethanol to make the alcohol content 80%, refrigerate at 4-8°C for 48 hours, filter with filter paper, recover ethanol from ...
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