Pharmaceutical composition for treating xerophthalmia as well as preparation method and application thereof

A composition and dry eye technology, applied in the direction of drug combinations, pharmaceutical formulas, active ingredients of hydroxyl compounds, etc., can solve problems such as easy to repeat, can not be cured, unsatisfactory curative effect, etc., to achieve easy clinical promotion and use, and less toxic and side effects Effect

Inactive Publication Date: 2019-06-11
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The current treatment methods can only relieve local symptoms, but cannot cure them.

Method used

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  • Pharmaceutical composition for treating xerophthalmia as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1, the preparation of medicine of the present invention

[0023] Formula: 0.35 grams of Scutellaria baicalensis, 0.35 grams of Coptis chinensis, 0.35 grams of Cortex Phellodendri, 0.35 grams of mint, 0.7 grams of Budisma japonica, 1.05 grams of gardenia, 0.21 grams of borneol, and 1.05 grams of ghost needle grass.

[0024] Preparation method: Weigh each raw material according to the formula, pulverize, sieve, mix, decoct with water, concentrate and granulate into granules.

[0025] Method of use: Take the medicinal composition, add 12 times the amount of water to decoct, and use 50-60°C hot medicinal steam to fumigate the patient's eyes with traditional Chinese medicine for 10-15 minutes.

Embodiment 2

[0026] Embodiment 2, the preparation of medicine of the present invention

[0027] Formula: 0.65 grams of Scutellaria baicalensis, 0.65 grams of Coptis chinensis, 0.65 grams of Cortex Phellodendri, 0.65 grams of mint, 1.3 grams of Budisma japonica, 1.95 grams of gardenia, 0.39 grams of borneol, and 1.95 grams of ghost needle grass.

[0028] Preparation method: Weigh each raw material according to the formula, crush, sieve, mix, add water to decoct, and refine honey into pills.

[0029] Method of use: Take the medicinal composition, add 10 times the amount of water to decoct, and use 50-60°C hot medicinal steam to fumigate the patient's eyes with traditional Chinese medicine for 10-15 minutes.

Embodiment 3

[0030] Embodiment 3, the preparation of medicine of the present invention

[0031] Recipe: 0.5 grams of Scutellaria baicalensis, 0.5 grams of Coptis chinensis, 0.5 grams of Cortex Phellodendri, 0.5 grams of mint, 1 gram of Budisma japonica, 1.5 grams of gardenia, 0.3 grams of borneol, and 1.5 grams of ghost needle grass.

[0032] Preparation method: Weigh each raw material according to the formula, crush, sieve, and mix evenly to obtain.

[0033] Method of use: Take the medicinal composition, add 10 times the amount of water to decoct, and use 50-60°C hot medicinal steam to fumigate the patient's eyes with traditional Chinese medicine for 10-15 minutes.

[0034] The beneficial effects of the present invention are illustrated below through test examples.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating xerophthalmia. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 0.35 to 0.65 part of baikal skullcap roots, 0.35 to 0.65 part of goldthread roots, 0.35 to 0.65 part of phellodendron bark, 0.35 to 0.65 part of mint, 0.7 to 1.3 parts of butterflybush flowers, 1.05 to 1.95 parts of cape jasmine fruits, 0.21 to 0.39 part of borneol and 1.05 to 1.95 parts of spanishneedles herb. In the pharmaceutical composition, the baikal skullcap roots, goldthread roots and phellodendron bark clear heat and dryness-heat; the mint, butterflybush flowers and cape jasmine fruits clear the liver and improve eyesight; the borneol increases the biological permeability of the cornea; the spanishneedles herb has a targeting effect on the xerophthalmia. The pharmaceutical composition is a fumigating compound preparation, has the effects of nourishing yin, moistening dryness, moistening and improving eyesight, has a remarkable effect on treating xerophthalmia and is suitable for clinical popularization and application.

Description

technical field [0001] The invention specifically relates to a pharmaceutical composition for treating dry eye, a preparation method and application thereof. Background technique [0002] Dry eye, also known as xerophthalmia, is a general term for a variety of diseases that are characterized by abnormal tear quality or quantity or dynamics that lead to decreased tear film stability, accompanied by ocular discomfort and / or ocular surface tissue lesions. Common symptoms include dry eyes, easy fatigue, itchy eyes, foreign body sensation, burning sensation, sticky secretions, fear of wind, photophobia, and sensitivity to external stimuli; sometimes the eyes are too dry, and there is basically insufficient tear fluid, which stimulates the reflex In severe cases, the eyes will be red and swollen, congested, keratinized, and the corneal epithelium is broken and there are filaments adhered. This kind of damage can cause keratoconjunctival lesions and affect vision over time. [000...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P27/02A61K31/045
Inventor 李娟金荣疆李梦晓刘栖岑何明星刘丹阳石丽红钟冬灵叶静
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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