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Plant extract composition having efficacy of removing acnes and preparation method of plant extract composition

A technology of plant extracts and compositions, applied in the directions of drug combinations, preparations for skin care, pharmaceutical formulations, etc., can solve the problems of inability to large-scale production, poor quality controllability, low willingness to use, etc., and achieve controllable and stable product quality. , Increase the effect of secondary utilization and sufficient supply of raw materials

Pending Publication Date: 2019-06-07
SHANGHAI JAKA BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, most of the products of cosmetic companies are concept products with no effect. Even the products of well-known manufacturers mainly add salicylic acid and Piaoning. The disadvantages are single effect, strong irritation, and large rebound; Traditional Chinese medicine hospital preparations (mostly western medicines are hormones) have complex components, poor quality controllability, difficulty in supplying a large number of raw materials (especially precious medicinal materials), and cannot be mass-produced. The scope of application is severely limited

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] (1) Weigh 100g of raw materials according to the following mass ratio: 1g of pomegranate peel, 1g of magnolia bark peel and 98g of mangosteen fruit peel, soak and extract with 500g of 80% ethanol aqueous solution at 80°C, and the number of extractions is 1 times, the time of soaking and extracting each time was controlled at 48h, and combined to obtain ethanol extract;

[0029] (2) Filter and concentrate the ethanol extract obtained in step (1) to 10 times, and use a macroporous adsorption resin for purification and elution. The eluent used in the elution step is ethanol aqueous solution with a volume percentage of 10%. liquid;

[0030] (3) Add 0.5g chitosan to 100mL glacial acetic acid aqueous solution containing 1mL glacial acetic acid and stir evenly to obtain a chitosan solution; add the eluate obtained in step (2) to the eluate at 45°C 1.0% chitosan solution, stirred evenly, then added activated carbon, stirred evenly, left standstill for 12h, collected the first ...

Embodiment 2

[0034] (1) Weigh 100g of raw materials according to the following mass ratio: 98g of pomegranate peel, 1g of magnolia bark peel and 1g of mangosteen fruit peel, soak and extract with 2000g of 10% ethanol aqueous solution at a temperature of 30°C, and the extraction times are 3 times, the time of soaking and extracting each time is controlled at 2h, and the ethanol extract is obtained by merging;

[0035] (2) Filter and concentrate the ethanol extract obtained in step (1) to 50 times, and use macroporous adsorption resin for purification and elution. The eluent used in the elution step is ethanol aqueous solution with a volume percentage of 95%. liquid;

[0036] (3) Add 2.0g chitosan to 100mL glacial acetic acid aqueous solution containing 1mL glacial acetic acid and stir evenly to obtain a chitosan solution; add the eluent obtained in step (2) to the eluent at a temperature of 70°C 6.0% chitosan solution, stirred evenly, then added gac, stirred evenly, left standstill for 12h...

Embodiment 3

[0040] (1) Weigh 100g of raw materials according to the following mass ratio: 1g of pomegranate peel, 98g of magnolia bark peel and 1g of mangosteen fruit peel, soak and extract with 1000g of 65% ethanol aqueous solution at 55°C, and the extraction times are 2 times, the time of soaking and extracting each time is controlled at 24h, and the ethanol extract is obtained by merging;

[0041] (2) Filter and concentrate the ethanol extract obtained in step (1) to 30 times, and use macroporous adsorption resin for purification and elution. The eluent used in the elution step is ethanol aqueous solution with a volume percentage of 55%. liquid;

[0042] (3) Add 1.5g chitosan to 100mL glacial acetic acid aqueous solution containing 1mL glacial acetic acid and stir evenly to obtain a chitosan solution; add the eluent obtained in step (2) to the eluent at a temperature of 50°C 2.5% chitosan solution, stirred evenly, then added gac, stirred evenly, left standstill for 12h, collected the ...

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Abstract

The invention relates to the technical field of cosmetics, in particular to a plant extract composition having efficacy of removing acnes and a preparation method of the plant extract composition. Byusing the total mass of the plant extract composition having the efficacy of removing acnes as a reference, the plant extract composition having the efficacy of removing acnes comprises the followingcomponents in percentage by mass of 1-98% of pomegranate rinds, 1-98% of cortex magnoliae officinalis bark and 1-98% of mangosteen peel. The plant extract composition has the effects of efficiently controlling oil, and efficiently resisting inflammation, is small in skin irritability, low in cost, simple in technology, controllable and stable in product quality, light in color, light in smell, free from obvious formula contraindication, broad in practicability, natural and safe, and can practically meet requirements of consumers for products capable of really restraining and removing acnes.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a plant extract composition with anti-acne effect and a preparation method thereof. Background technique [0002] Acne (also known as whelk) is a kind of disfiguring skin lesion, which affects the quality of life and mental health of the majority of teenagers, and the age group of acne also extends to 30-40 years old. In order to meet the demand for acne treatment relief, many cosmetic companies and hospitals have launched their own products or in-hospital preparations. Among them, most of the products of cosmetic companies are concept products with no effect. Even the products of well-known manufacturers mainly add salicylic acid and Piaoning. The disadvantages are single effect, strong irritation, and large rebound; Traditional Chinese medicine hospital preparations (mostly western medicines are hormones) have complex components, poor quality controllability, difficulty in s...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61Q19/00A61Q17/00A61P17/10A61P29/00
Inventor 王光寅卢伊娜谢红
Owner SHANGHAI JAKA BIOTECH CO LTD
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