Traditional Chinese medicine composition for treating aseptic necrosis of femoral head

A femoral head necrosis and composition technology, which is applied in the field of medicine, can solve the problems of no aseptic femoral head necrosis biological activity or clinical application, and achieve the effects of significant indicators, improvement of various indicators, and excellent therapeutic effect

Inactive Publication Date: 2019-05-07
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] So far, there is no research on the biological activity or clinical application of Mailuoshutong Granules in the treatment of aseptic femoral head necrosis

Method used

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  • Traditional Chinese medicine composition for treating aseptic necrosis of femoral head
  • Traditional Chinese medicine composition for treating aseptic necrosis of femoral head
  • Traditional Chinese medicine composition for treating aseptic necrosis of femoral head

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0114] Embodiment 1 Mailuoshutong Granules

[0115] Prescription of Chinese medicine combination group:

[0116]

[0117] Preparation:

[0118] 1) Take honeysuckle, herb, scrophulariaceae, angelica, and white peony in a multifunctional extraction tank for steam distillation to obtain medicinal residues, medicinal liquid, and crude volatile oil; redistill the crude volatile oil to obtain refined volatile oil ,

[0119] 2) adding absolute ethanol to the refined volatile oil obtained in step 1), and mixing evenly to obtain an ethanol volatile oil solution, which is stored in an airtight container;

[0120] 3) Take the astragalus, cortex phellodendri, coix seed, licorice and 1 / 2 of the prescription amount of leech, centipede, scorpion and the dregs obtained in step 1) and decoct twice with water for 1.5 hours and 1 hour respectively. hour, combine the decoction, filter, take the medicinal solution obtained in step 1) and combine and concentrate it, add ethanol and let it sta...

Embodiment 2

[0122] Embodiment 2 Mailuoshutong tablet

[0123] Prescription of Chinese medicine combination group:

[0124]

[0125] 1) Take honeysuckle, herb, scrophulariaceae, angelica, and white peony in a multifunctional extraction tank for steam distillation to obtain medicinal residues, medicinal liquid, and crude volatile oil; redistill the crude volatile oil to obtain refined volatile oil ,

[0126] 2) adding absolute ethanol to the refined volatile oil obtained in step 1), and mixing evenly to obtain an ethanol volatile oil solution, which is stored in an airtight container;

[0127] 3) Take astragalus, Phellodendron Phellodendri, coix seed, licorice and 1 / 2 of the prescription amount of leech, centipede, scorpion and the dregs obtained in step 1) and decoct once in water for 3 hours, then filter the decoction , taking step 1) the obtained medicinal solution is combined with it and concentrated, after cooling, add ethanol and let it stand for more than 12 hours to make it ful...

Embodiment 3

[0129] Embodiment 3 Mailuoshutong dripping pills

[0130] Prescription of Chinese medicine combination group:

[0131]

[0132] 1) Take honeysuckle, atractylodes atractylodes, Radix Scrophulariae, Radix Scrophulariae Scrophulariae, Radix Scrophulariae Scrophulariae, and Radix Paeoniae Alba in a multifunctional extraction tank for steam distillation to obtain medicinal residues, medicinal liquid, and crude volatile oil; redistill the crude volatile oil to obtain refined volatile oil;

[0133] 2) adding absolute ethanol to the refined volatile oil obtained in step 1), and mixing evenly to obtain an ethanol volatile oil solution, which is stored in an airtight container;

[0134] 3) Take astragalus, cortex phellodendri, coix seed, licorice and 1 / 2 prescription amount of leech, centipede, scorpion and the dregs obtained in step 1) and decoct twice with water for 1.5 hours and 1 hour respectively. Combine the decoctions, filter, take the medicinal solution obtained in step 1) a...

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Abstract

The present invention relates to a traditional Chinese medicine composition for treating aseptic necrosis of femoral head and belongs to the field of medicine. The traditional Chinese medicine composition is prepared from radix astragali, honeysuckle, cortex phellodendri, rhizoma atractylodis, radix scrophulariae, Chinese angelica, white paeony root, coix seeds, etc. Pharmacodynamic tests show that the composition has a significant relieving function in dexamethasone-induced aseptic necrosis of femoral head in rabbits, and at the same time clinical trials show that the composition has a significant therapeutic effect on the aseptic necrosis of femoral head. The traditional Chinese medicine composition is comprehensive in action and low in toxic and side effects when being used for treatingthe aseptic necrosis of femoral head, has a better therapeutic effect than existing therapeutic drugs, and has broad market prospects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating aseptic femoral head necrosis, which belongs to the field of medicine. Background technique [0002] The causes of aseptic necrosis of the femoral head (ANFH) mainly include traumatic and non-traumatic two categories. Traumatic factors used to be the primary cause of the disease. With the improvement of people's living standards, the proportion of non-traumatic factors is increasing year by year, becoming the main cause of the disease, mainly including hormones, alcohol, genetic factors and other unknown factors . The common final result of these factors is the interruption of the effective blood supply of the femoral head, leading to a series of complex pathological processes of the death of the active components of the bone and subsequent repair. Related theories mainly include the theory of blood stagnation, the theory of abnormal differentiation of bone marrow stroma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P19/08A61K35/62
Inventor 张贵民赵云杨鉴
Owner LUNAN PHARMA GROUP CORPORATION
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