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Method for Measuring Tissue Oxygen Saturation Using Single Distance Light Source-Detector Pair

A technology of distance light source and detector, applied in the field of blood oxygen measurement, can solve the problem of increasing the cost of the instrument, the size of the optical probe, etc., and achieve the effect of reducing the cost

Active Publication Date: 2021-07-16
ZHONGBEI UNIV
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Problems solved by technology

But multiple S-D pairs increase the cost of the instrument and the size of the optical probe, making it difficult to perform measurements on tissues with small size or large curvature (e.g., mouse brain, human breast)

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  • Method for Measuring Tissue Oxygen Saturation Using Single Distance Light Source-Detector Pair
  • Method for Measuring Tissue Oxygen Saturation Using Single Distance Light Source-Detector Pair
  • Method for Measuring Tissue Oxygen Saturation Using Single Distance Light Source-Detector Pair

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Embodiment Construction

[0029] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are part of the embodiments of the present invention, rather than All the embodiments; based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts all belong to the protection scope of the present invention.

[0030] Such as figure 1 As shown, the embodiment of the present invention provides a method for measuring tissue blood oxygen saturation using a single-distance light source-detector pair, including the following steps:

[0031] S1, configuration absorption coefficients are μ a0 (λ i ) and (1-α)μ a0 (λ i ) of two phantom models.

[0032] Among them, α represents the change rate of the absorption coeff...

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Abstract

The present invention relates to the technical field of blood oxygen measurement in biomedical engineering, and proposes a method for measuring blood oxygen saturation using a single-distance light source-detector pair, including the following steps: S1, configuring two phantoms with known absorption coefficients Model; S2, measuring the light intensity of the two phantom models at wavelength λ1 and wavelength λ2 by single-distance light source-detector; S3, measuring the light intensity of the sample at wavelength λ1 and wavelength λ2 by single-distance light source-detector; S4. Calculate the absorption coefficients of the samples at the two wavelengths according to the measured light intensity values; S5. Calculate the concentrations of oxyhemoglobin and deoxyhemoglobin in the samples according to the absorption coefficients at the two wavelengths. The present invention can quantify blood oxygen saturation by measuring optical signals with a single-distance light source-detector pair, simplifies the measuring instrument, has high accuracy, and can be widely used in the technical field of blood oxygen measurement.

Description

technical field [0001] The invention relates to the technical field of blood oxygen measurement in biomedical engineering, in particular to an application method of an improved MBLL algorithm in single-distance S-D pair measurement of blood oxygen saturation. Background technique [0002] The importance of oxygen to maintain physiological activities is self-evident. The oxygen carried in the blood is supplied to tissues through the blood flow of the microvasculature. Many diseases, such as ischemic stroke, cancer, and peripheral arterial disease, can significantly alter oxygen saturation status. Therefore, monitoring oxygenation status is crucial for understanding pathophysiology as well as disease diagnosis and treatment. [0003] However, currently available techniques for assessing the oxygenation status of tissues in vivo are limited. Oxygen partial pressure (PO 2 ) is a technique to quantify oxygen pressure in the invasive mode, which is unfavorable for healthy peopl...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/31
CPCG01N21/314G01N2021/3144
Inventor 桂志国尚禹张鹏程白静朱其森刘佳鑫
Owner ZHONGBEI UNIV
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