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Dose optimization guided TPS (transaction per second) automatic iterative optimization algorithm

An iterative optimization and dose technology, applied in the medical field, can solve problems such as time-consuming and labor-intensive, and achieve the effect of solving inconsistent dose distribution and reducing the time for making plans

Active Publication Date: 2019-03-22
SUZHOU LINATECH MEDICAL SCI & TECH CO LTD
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Problems solved by technology

This process reference figure 1 , which is especially cumbersome for complex cases, and may require the planner to iterate many times manually, which is time-consuming and labor-intensive

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  • Dose optimization guided TPS (transaction per second) automatic iterative optimization algorithm
  • Dose optimization guided TPS (transaction per second) automatic iterative optimization algorithm
  • Dose optimization guided TPS (transaction per second) automatic iterative optimization algorithm

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Embodiment Construction

[0066] Preferred embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings.

[0067] In order to achieve the purpose of the present invention, in some embodiments of an optimal dose-guided TPS automatic iterative optimization algorithm,

[0068] The traditional two-step IMRT (Intensity modulated radiation therapy) planning process generally includes two steps: field intensity map optimization and irradiation implementation. The optimized dose distribution of the field intensity map is an ideal dose distribution. If grating is used for treatment, the optimized field intensity map needs to be divided into subfields to obtain a series of subfields. Due to the characteristics and physical limitations of the grating, such as the maximum speed of the grating movement, the parameters of the grating penumbra, etc., there is a certain difference between the dose distribution of the actual irradiation and the optimized distribut...

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Abstract

The invention discloses a dose optimization guided TPS (transaction per second) automatic iterative optimization algorithm which includes the steps: first, calculating the difference of the dose and the optimization result of each point in each organ according to fractionated dose as optimization engine input to obtain strength map contribution of the difference; second, subtracting the strength map of the difference from an original optimized strength map to serve as strength map input of sub-domain segmentation to obtain iterated sub-domains, and calculating the dose; finally, repeating thewhole process, enabling final dose distribution to be approximate to the optimized dose to obtain expected dose distribution. The step of sub-domain segmentation is taken into the whole optimization process, dose deviation caused by sub-domain segmentation is continuously corrected, planning quality can be remarkably improved, and plan making efficiency is accelerated.

Description

technical field [0001] The invention belongs to the field of medical technology, and mainly relates to an optimization algorithm for inverse intensity-modulated radiotherapy, in particular to an optimized dose-guided TPS automatic iterative optimization algorithm. Background technique [0002] Intensity-modulated radiation therapy (IMRT), as a type of radiotherapy, adjusts the beam intensity according to the three-dimensional shape of the target area and the anatomical relationship between the organs at risk and the target area, so that the distribution of radiation dose is consistent with the shape of the target area, and the radiation dose received in the target area is consistent with the target area. The uniformly distributed high dose ensures the killing of tumor cells, and at the same time enables normal tissues to receive a lower dose of irradiation, so as to protect normal organs and reduce adverse reactions. [0003] The traditional IMRT planning process generally i...

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Application Information

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IPC IPC(8): A61N5/10
CPCA61N5/1002A61N5/1031A61N5/1049A61N5/1071A61N2005/1054
Inventor 文虎儿鞠垚姚毅
Owner SUZHOU LINATECH MEDICAL SCI & TECH CO LTD
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