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Compound traditional Chinese medicine for treating liver fibrosis

A compound traditional Chinese medicine, liver fibrosis technology, applied in the digestive system, drug combination, pharmaceutical formula and other directions, can solve the problem of inaccurate efficacy of western medicine, achieve the protection of liver cells, improve liver function and liver tissue hydroxyproline level, The effect of regulating collagen metabolism

Inactive Publication Date: 2019-02-22
厦门市中医院 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Common countermeasures for the treatment of liver fibrosis are to treat the primary disease, prevent liver damage, reduce inflammation, and inhibit the activation and proliferation of stellate cells, etc., but the curative effect of western medicine is not yet clear

Method used

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  • Compound traditional Chinese medicine for treating liver fibrosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The granule dosage form of the compound Chinese medicine of embodiment 1 treatment liver fibrosis

[0017] Using the conventional method of preparing granules, take 1 part of saponin japonicus, 1 part of fried Atractylodes macrocephala, 1 part of Codonopsis pilosula, 1 part of astragalus, 1 part of red peony root, 1 part of salvia miltiorrhiza, 1 part of angelica, 1 part of peach kernel, 1 part of curcuma, and 1 part of vinegar turtle. 1 part of A, the amount of water added is 10 times and 8 times respectively, the first extraction is 2h, the second extraction is 1.5h, filtered, the filtrate is combined, concentrated, dried, crushed, added appropriate amount of excipients, mixed, granulated, and sieved , dried, and a compound Chinese medicine for treating liver fibrosis in granular dosage form is prepared.

Embodiment 2

[0018] The tablet dosage form of the compound Chinese medicine of embodiment 2 treatment liver fibrosis

[0019] Using the conventional method of preparing granules, take 1.5 parts of saponins, 1.5 parts of fried Atractylodes macrocephala, 1.5 parts of codonopsis, 2 parts of astragalus, 1 part of red peony root, 1 part of salvia miltiorrhiza, 1 part of angelica, 1 part of peach kernel, 1 part of curcuma, and 1 part of vinegar turtle. 1 part of A, the amount of water added is 10 times and 8 times respectively, the first extraction is 2h, the second extraction is 1.5h, filtered, the filtrate is combined, concentrated, dried, crushed, added appropriate amount of excipients, mixed, granulated, and sieved , dried, and a compound Chinese medicine for treating liver fibrosis in granular dosage form is prepared.

Embodiment 3

[0020] The capsule dosage form of the compound Chinese medicine of embodiment 3 treatment liver fibrosis

[0021] Using the conventional method of preparing granules, take 0.5 parts of saponins, 2 parts of fried Atractylodes macrocephala, 0.5 parts of codonopsis, 3 parts of astragalus, 0.5 parts of red peony, 1 part of salvia miltiorrhiza, 0.3 parts of angelica, 1 part of peach kernel, 0.5 part of curcuma, and 0.5 part of vinegar turtle. 1.5 parts of A, the amount of water added is 10 times and 8 times respectively, the first extraction is 2 hours, the second extraction is 1.5 hours, filtered, combined filtrate, concentrated, dried, crushed, add appropriate amount of excipients, mix well, granulate, and sieve , dried, and a compound Chinese medicine for treating liver fibrosis in granular dosage form is prepared.

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Abstract

The invention discloses a compound traditional Chinese medicine for treating liver fibrosis, and relates to compound traditional Chinese medicines. The compound traditional Chinese medicine comprises,in weight percent, 0.5-2% of spina gleditsiae, 0.5-2% of stir-fried largehead atractylodes rhizomes, 0.5-2% of tangshen roots, 1-3% of membranous milkvetch roots, 0.5-1.5% of common peony roots, 0.5-1.5% of red-rooted salvia roots, 0.3-1% of Chinese angelica roots, 0.3-1% of peach seeds, 0.5-1.5% of turmeric rhizomes and 0.5-1.5% of vinegar turtle. The compound traditional Chinese medicine is prepared from conventional pharmaceutical excipients by a conventional method in the field of pharmacy. The compound traditional Chinese medicine for treating the liver fibrosis can be taken after beingdetected or extracted by water or ethyl alcohol. The medicine can be prepared into medically acceptable oral preparations such as tablets, capsules, granules and the like, and pharmacodynamical research shows that the medicine has the functions of invigorating spleen, supplementing qi, activating blood and dissolving stasis and is an effective and special medicine for treating liver fibrosis.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine, in particular to a compound traditional Chinese medicine for treating liver fibrosis. Background technique [0002] Liver fibrosis refers to the abnormal proliferation of connective tissue in the liver caused by various pathogenic factors. Any liver injury has a process of liver fibrosis in the process of liver repair and healing. If the damage factors cannot be removed for a long time, the fibrosis process will develop into liver cirrhosis if it continues for a long time. Therefore, blocking or reversing liver fibrosis is of great significance for the prevention and treatment of liver cirrhosis. Common countermeasures for the treatment of liver fibrosis include treating the primary disease, preventing liver damage, reducing inflammation, and inhibiting the activation and proliferation of stellate cells. However, traditional Chinese medicine has shown obvious advantages in the interven...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/16A61K35/586
CPCA61K35/586A61K36/232A61K36/284A61K36/344A61K36/481A61K36/483A61K36/537A61K36/65A61K36/71A61K36/736A61K36/9066A61P1/16A61K2300/00
Inventor 陈少东梁惠卿
Owner 厦门市中医院
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