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Externally-applied traditional Chinese medicine preparation for accelerating healing of chronic skin ulcer wounds and preparation method thereof

A technology for chronic skin ulcer and wound healing, applied in the field of traditional Chinese medicine

Active Publication Date: 2019-02-12
青岛市市南区人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the late 1990s, molecular biology developed by leaps and bounds. The process of wound repair was studied from the perspective of molecular and cell physiology. A large number of growth factor products for the treatment of chronic ulcers emerged. At the same time, physical assisted therapy was studied, but it has not yet There is a single consensus or guideline for the treatment of chronic ulcers

Method used

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  • Externally-applied traditional Chinese medicine preparation for accelerating healing of chronic skin ulcer wounds and preparation method thereof
  • Externally-applied traditional Chinese medicine preparation for accelerating healing of chronic skin ulcer wounds and preparation method thereof
  • Externally-applied traditional Chinese medicine preparation for accelerating healing of chronic skin ulcer wounds and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0160] The preparation of embodiment 1 Chinese medicine plaster

[0161] 1. Technical essentials and matters needing attention

[0162] One pill and two oils, the plaster is thick, three times up and three times, boiled to remove slag, dripping water to form beads, away from the fire, the pill is ripe, good fortune, cold water underground, its shape is black like lacquer, hot is soft, cold is hard, paste It sticks when you pull it out.

[0163] The technical essentials that should be mastered in boiling plaster:

[0164] 1. Do not use too much or too little explosive. If it is not enough, the effect will be hard to find. If it is too much, it will affect the viscosity of the plaster.

[0165] 2. Pay attention to controlling the heat and dosage when lowering the elixir. Low temperature will affect the elixir oil compounding and its color will not be lustrous. It is flammable in high fire, and the paste is tender if the amount of Dan is small, and it is easy to lose and does ...

Embodiment 2

[0185] Example 2 typical case

[0186](2 beds) Patient Fan Moumou, female, 80 years old, hospital number: 8000008751, People's Hospital of Shinan District, Qingdao. No. 44, Jiading Road, Shibei District, Qingdao. First visit on 2018-08-27. The patient was admitted to the hospital due to "multiple ruptures on the left calf and both feet for more than 2 months". More than two months ago, the patient had ulcers on the dorsum of both feet due to trauma, and had been changing dressings with povidone iodine on his own without any special treatment. Half a month ago, ulcers appeared one after another on the left calf and heels. , Diagnosed as "type 2 diabetic foot disease" admitted to the hospital. Physical examination: both feet were swollen, the second toe of the left foot had an ulcerated surface of about 1cm*1cm, and the bone was exposed. The size of the left dorsal ulcer is about 10cm*8cm, the size of the left heel ulcer is about 5cm*5cm, the size of the right dorsal ulcer i...

Embodiment 3

[0187] Embodiment 3: typical case

[0188] (5 beds) Patient Zhou Moumou, male, 63 years old, hospital number 8000003591. Tuandao 2nd Road, South District, Qingdao. First visit on 2018-07-20. The patient came to the clinic for more than 20 days due to "infection and ulceration of the right foot. The fourth toe of the patient's right foot was ruptured 20 days ago. He did not pay attention to it and changed the dressing on his own. The infection aggravated, the toe became black and necrotic, and gradually developed to the proximal end. Necrosis, accompanied by fever, had been treated in the western branch of the municipal hospital, and was diagnosed as "type 2 diabetic foot gangrene" by relevant examinations, and treated with anti-infection, hypoglycemia, and dressing changes (specifically unknown), the condition further developed, and the ulcerated surface Up to the soles of the feet. Today, he was admitted to the hospital with "type 2 diabetic foot gangrene". Mild pitting ede...

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Abstract

The invention relates to an externally-applied traditional Chinese medicine preparation for accelerating healing of chronic skin ulcer wounds and a preparation method thereof. According to the preparation, root of angelica sinensis(oliv.)diels, frankincense, commiphora myrrha engl.[c.molmol engl.], daemonorops draco blume., flower of carthamus tinctorius l. and dried body of eupolyphaga sinensis walker are used as monarch drugs capable of promoting blood circulation, removing obstruction in collaterals and relieving pain; unprocessed rehmannia root, root of paeonia veitchii lynch, root of scrophularia ningpoensis hemsl., root of rheum palmatum L. and root of lithospermum erythrorhizon sieb.et zucc. are used as ministerial drugs capable of cooling blood, relieving pain, detoxifying, and reinforcing the pain relieving effects of the monarch drugs; root of sophora flavescens ait. and cortex of phellodendron chinense Schneid. are capable of clearing heat and drying dampness; root of angelica dahurica (Fisch.ex Hoffm.) Benth.et Hook.f., root of notopterygium incisum ting ex h.t.chang and angelica pubescens Maxim.f.biserrata Shan et Yuan have the effects of dispelling wind and eliminating dampness; the root of sophora flavescens ait., the cortex of phellodendron chinense schneid., the root of angelica dahurica(Fisch.ex Hoffm.) Benth.et Hook.f., the root ofnotopterygium incisum tingex h.t.chang and the root of angelica pubescens Maxim.f.biserrata Shan et Yuan can cooperate with one another to remove damp heat toxin and fire toxin formed when circulation of qi and blood is unsmooth and qi and blood overflow outside veins due to stasis and blockage of blood vessels; the damp heat toxin and fire toxin are accumulated subcutaneously to form lumps; tuber of ampelopsis japonica(Thunb.)Makino, momordica cochinchinensis(Lour.)Spreng. and forsythia suspensa(thunb.)vahl are used to assist in clearing heat, removing stasis and diminishing swelling; the sophora flavescens ait., thephellodendron chinense schneid., the angelica dahurica(fisch.ex hoffm.)benth.et hook.f., the notopterygium incisum ting ex h.t.chang, angelica pubescens maxim.f.biserrata shan et yuan, the ampelopsisjaponica(thunb.)makino, seed of momordica cochinchinensis(Lour.)Spreng. and fruit of forsythia suspensa(Thunb.)Vahl are jointly used as adjuvant drugs; cinnamomum cassia presl, tuber of lindera aggregata(Sims)Kosterm. and borneol are capable of inducing menstruation to relieve menalgia and reinforcing the pain relieving effects of the monarch drugs; bletilla striata(Thunb.)Reichb.f. is capable ofdiminishing swelling and promoting granulation; the cinnamomum cassia presl, the lindera aggregata(sims)kosterm., the borneol and the rhizome of bletilla striata(Thunb.)Reichb.f. are jointly used as envoy drugs. Through treatment and follow-up on multiple patients with diabetic foot gangrene and decubital ulcer, the total effective rate is 100%.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to an external Chinese medicine preparation for promoting wound healing of chronic skin ulcer and a preparation method thereof. Background technique [0002] Skin ulcers are local tissue defects caused by various reasons. Wounds that have not healed for more than 2 weeks are called chronic skin ulcers, and those that have not healed for more than 1 month are chronic refractory skin ulcers. Chronic skin ulcers belong to the categories of "refractory sores", "ectanitis", "necrosis" and "seat sores" in traditional Chinese medicine, including vascular ulcers (arteriosclerotic ulcers, varicose ulcers), traumatic ulcers, infection ulcers, chemical ulcers, radiation ulcers, pressure ulcers, neurotrophic ulcers, diabetic ulcers, snakebite ulcers, ulcers on scars after burns, etc. The disease has a long course and is difficult to cure, seriously affecting t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P17/02A61K35/64A61K31/045
CPCA61K36/889A61K36/896A61K36/898A61P17/02A61K31/045A61K35/63A61K35/64A61K36/232A61K36/237A61K36/286A61K36/30A61K36/324A61K36/328A61K36/42A61K36/489A61K36/54A61K36/634A61K36/65A61K36/708A61K36/71A61K36/756A61K36/804A61K36/808A61K36/87A61K2236/35A61K2300/00
Inventor 董学刚宋培铎汤晓南高岩于方举郑鹏马飞飞滕馨慧庄倩潘茹
Owner 青岛市市南区人民医院
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