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Iridium complex with chemotherapy and phototherapy antitumor effects at the same time and preparation method and application thereof

An anti-tumor effect, iridium complex technology, applied in the medical field, to achieve the effect of simple preparation method, molecular stability and targeted effect

Active Publication Date: 2019-01-22
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Dozens of anti-tumor drugs currently used in clinical chemotherapy or adjuvant, only have a good curative effect on the treatment of some tumors

Method used

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  • Iridium complex with chemotherapy and phototherapy antitumor effects at the same time and preparation method and application thereof
  • Iridium complex with chemotherapy and phototherapy antitumor effects at the same time and preparation method and application thereof

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Embodiment Construction

[0024] The present invention will be further described in detail below in conjunction with the embodiments, so that those skilled in the art can implement it with reference to the description.

[0025]

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Abstract

The invention discloses an iridium complex with chemotherapy and phototherapy antitumor effects at the same time and a preparation method and application thereof. The iridium complex with the chemotherapy and phototherapy antitumor effects at the same time is characterized in that a chemical structural formula of the iridium complex with the chemotherapy and phototherapy antitumor effects at the same time is as shown in the description. The iridium complex with the chemotherapy and phototherapy antitumor effects at the same time can be used for preparing medicines for treating cancer and hypertension, has the chemotherapy and phototherapy effects at the same time, and has good biological activity; the iridium complex with the chemotherapy and phototherapy antitumor effects at the same timehas a conjugated system structure, and molecules are stabler; the preparation method is simple, and the cost is low.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to an iridium complex having both chemotherapy and phototherapy anti-tumor effects, a preparation method and application thereof. Background technique [0002] Cancer is one of the most important diseases that endanger human health, and there is still no effective treatment. Most of the antineoplastic drugs currently used clinically are nucleoside drugs, which have similar antitumor spectrum and have strong toxic and side effects. On the other hand, some tumor cell lines are prone to drug resistance to clinically used drugs, and tumor cell lines are also prone to mutation. Therefore, the development of anti-tumor drugs that can overcome drug resistance or have broad-spectrum activity has attracted attention. The anti-tumor spectrum and anti-tumor mechanism of metal complexes are different from nucleoside drugs, which has aroused the interest of scientific researchers. Dozens of a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07F15/00A61K31/555A61K41/00A61P35/00A61P9/12
CPCA61K31/555A61K41/0057A61P9/12A61P35/00C07F15/0033
Inventor 李培源苏炜霍丽妮陈睿
Owner GUANGXI UNIV OF CHINESE MEDICINE
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