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Method for detecting correlation between vitamin D metabolism and glycolmetabolism and placenta in diabetic pregnant women

A detection method, diabetes technology, applied in the field of detection of pregnant women, can solve the problems of aggravating VD in pregnant women, affecting VD metabolism in pregnant women, etc.

Inactive Publication Date: 2019-01-15
颜云华 +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

But so far, whether GDM will aggravate VD deficiency in pregnant women, and whether abnormal glucose metabolism in GDM will affect VD metabolism in pregnant women are still unclear.

Method used

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  • Method for detecting correlation between vitamin D metabolism and glycolmetabolism and placenta in diabetic pregnant women
  • Method for detecting correlation between vitamin D metabolism and glycolmetabolism and placenta in diabetic pregnant women

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Embodiment Construction

[0055] In order to make the object, technical solution and advantages of the present invention clearer, the present invention is described below through specific embodiments shown in the accompanying drawings. It should be understood, however, that these descriptions are exemplary only and are not intended to limit the scope of the present invention. Also, in the following description, descriptions of well-known structures and techniques are omitted to avoid unnecessarily obscuring the concept of the present invention.

[0056] like figure 1 Shown, this specific embodiment adopts following technical scheme: its detection method is:

[0057] 1) Selection of research objects:

[0058] Randomly select 100 cases of normal pregnant women and GDM patients hospitalized in obstetrics and gynecology department. All patients received basic surveys and routine laboratory examinations, balancing the individual conditions of all selected candidates such as age, income, ethnicity, educat...

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Abstract

The invention discloses a method for detecting correlation between vitamin D metabolism and glycolmetabolism and placenta in diabetic pregnant women, and relates to the technical field of pregnant women detection. The detection method thereof comprises the following steps: 1) selection of research objects; 2) collection of research data; 3) sample collection; 4) measurement of blood glucose metabolism related indicators; 5) measurement of blood VD metabolism related indicators; 6) placental morphology observation; 7) adipocytokines detection; 8) detection of placental insulin signaling pathwayrelated indicators; 9) detection of placenta VD metabolic pathway related indicators; 10) quality control; and 11) statistical analysis. The placenta provided by the invention can promote the development of GDM through various ways, and can also express the molecules necessary for metabolism of the VD system, so that the VD metabolism during pregnancy is changed, which is different from non-pregnant state, thereby further clearing about the development relationship between VD and GDM and providing new evidence for the prevention and treatment of GDM by VD so as to reduce the adverse pregnancyoutcome and improve the health of the population.

Description

technical field [0001] The invention relates to a correlation between vitamin D metabolism and glucose metabolism and a placenta detection method for pregnant women with gestational diabetes, belonging to the technical field of detection of pregnant women. Background technique [0002] Gestational diabetes mellitus (GDM) is one of the most common complications of pregnancy, which refers to abnormal glucose metabolism in varying degrees that occurs during pregnancy (excluding pre-pregnancy). In recent years, due to factors such as the delay of women's childbearing time, changes in lifestyle and dietary structure, and lack of nutritional knowledge, the incidence of GDM has shown an obvious upward trend all over the world. The International Diabetes Federation estimates that about 16.8% of pregnant women are in a state of hyperglycemia during pregnancy, of which 84% are GDM. The prevalence of GDM in my country is even more severe. The latest screening results of 17,186 pregna...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/66G01N33/82G01N33/96G01N33/543G01N33/68G01N33/74G01N21/76G01N21/84
CPCG01N33/66C12Q1/686G01N21/76G01N21/763G01N21/84G01N33/543G01N33/6863G01N33/689G01N33/74G01N33/82G01N33/96G01N2333/62G01N2333/715G01N2800/368C12Q2561/113
Inventor 颜云华戴楠
Owner 颜云华
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