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Nutritional composition for protecting the heart of a companion animal

A technology for companion animals and compositions, which is applied in the direction of drug combinations, animal feed, animal feed, etc., and can solve problems such as not necessarily easy and safe to use, side effects, and unsatisfactory solutions

Active Publication Date: 2021-08-17
SOC DES PROD NESTLE SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the use of these drugs is not necessarily easy and safe, and may also have side effects
Therefore, previous methods cannot satisfactorily address the DMVD problem on dogs

Method used

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  • Nutritional composition for protecting the heart of a companion animal
  • Nutritional composition for protecting the heart of a companion animal
  • Nutritional composition for protecting the heart of a companion animal

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0046] One aspect of the present disclosure is a method of treating DMVD in a companion animal suffering from degenerative mitral valve disease (DMVD). Another aspect of the present disclosure is a method of preventing DMVD in a companion animal at risk for DMVD. Yet another aspect of the present disclosure is a method of maintaining or improving cardiac health in a companion animal.

[0047] The method comprises orally administering to the dog a composition comprising medium chain triglycerides and optionally one or more of omega-3 fatty acids, vitamin E, magnesium, taurine, lysine, or sulfur-containing amino acids. The composition can be a pet food, such as a moist pet food, a semi-moist pet food, or a dry pet food, such as kibble.

[0048] Generally, the medium chain triglycerides can range from about 0.5% to about 60% by weight of the composition. In one aspect, the medium chain triglycerides can be from about 1% to about 20% by weight of the composition. In other aspec...

Embodiment 1

[0065] Example 1 - Heart Health Hybrid Study in Canines with DMVD

[0066] Nineteen healthy dogs and 21 dogs with a heart murmur were selected for a 6-month study. All dogs were examined using echocardiography by board-certified veterinary cardiologists and were identified as either healthy or with early degenerative mitral valve disease (DMVD). Dogs in each group were randomly divided into two dietary treatment groups based on age, sex, breed, weight, and murmur grade. The control diet, manufactured by Nestle Purina PetCare Company, provided complete and balanced nutrition to meet or exceed the requirements set forth by the Association of American Feed Control Officials (AAFCO). The test diet contained all the components of the control diet plus the following additional components: medium chain triglycerides (MCT) in an amount of 5.000% by weight, omega-3 fatty acids in an amount of 0.7489% by weight, lysine in an amount of 2.3000% by weight, Methionine and cysteine ​​in ...

Embodiment 2

[0071] Example 2 - Heart Health Hybrid Study in Canines with DMVD

[0072] Seven beagles and one miniature schnauzer were selected for the study and all dogs were examined using echocardiography by a board-certified veterinary cardiologist and classified as having degenerative mitral valve disease (DMVD). Dogs were randomly assigned into two dietary treatment groups. The control diet, manufactured by Nestle Purina PetCare Company, provided complete and balanced nutrition to meet or exceed the requirements set forth by the Association of American Feed Control Officials (AAFCO). The test diet contained the same ingredients as the control diet, except that it additionally contained 7% medium chain triglycerides (MCT). The diet was isocaloric and nitrogenous. Diets are shown in Table 1.

[0073] Table 1

[0074] Ingredients / Nutrients control diet test diet Medium Chain Triglycerides (MCT), % 0.0 7.0 Omega-3 fatty acids, % 0.8 0.8 Lysine, ...

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Abstract

The present invention discloses a method of treating DMVD in a companion animal with degenerative mitral valve disease (DMVD), a method of preventing DMVD in a companion animal at risk of DMVD, and a method of maintaining or improving heart health in a companion animal Methods. The method comprises orally administering to a companion animal a composition comprising medium chain triglycerides and optionally one or more of omega-3 fatty acids, vitamin E, lysine, taurine, magnesium, or sulfur-containing amino acids.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to US Provisional Application Serial No. 62 / 339,436, filed May 20, 2016, the disclosure of which is incorporated herein by reference in its entirety. Background technique [0003] The present disclosure generally relates to food compositions. More specifically, the present disclosure relates to compositions comprising medium chain triglycerides and methods comprising administering the compositions to companion animals. [0004] The mitral valve is located between the left atrium and left ventricle of the heart and is formed from thin flaps or leaflets of tissue that are attached to the muscles of the left ventricle by long tendon-like structures (chordae). The mitral valve helps regulate the flow of blood into and out of the heart and prevents backflow of blood into the atria. The leaflets open and close to regulate the flow of blood, but when dogs have degenerative mitral valve disease...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/23A61K31/202A61K31/185A61K31/198A61K31/20A61K31/205A61K31/355A61K33/14A61K45/06A23K50/40A61K9/00A61P9/00A61P43/00A23K10/00A23K20/158
CPCA61K45/06A61K31/185A61K31/198A61K31/20A61K31/202A61K31/205A61K31/23A61K31/355A61K33/14A23K10/00A23K20/158A23K50/40A61K47/12A61K47/14A61K47/183A23K20/174A23K20/142A23K20/24A23K20/30A23K50/48A61K47/20A61P3/02A61P43/00A61P9/00A61K2300/00A23L33/12A23L33/16A23V2002/00A61K9/0029
Inventor Q·李D·P·拉弗莱姆B·V·博勒X·许S·巴特纳格尔
Owner SOC DES PROD NESTLE SA
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