Nutritional compositions for cardciac protection in companion animals
A companion animal and composition technology, applied in the direction of drug combination, animal feed, animal feed, etc., can solve the problems that are not necessarily easy and safe to use, can not be solved satisfactorily, have side effects, etc.
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[0046] One aspect of the present disclosure is a method of treating DMVD in companion animals suffering from degenerative mitral valve disease (DMVD). Another aspect of the present disclosure is a method of preventing DMVD in companion animals at risk of DMVD. Yet another aspect of the present disclosure is a method of maintaining or improving the heart health of a companion animal.
[0047] The method includes orally administering to the dog a composition comprising medium chain triglycerides and any one or more of omega-3 fatty acids, vitamin E, magnesium, taurine, lysine, or sulfur-containing amino acids. The composition may be pet food, such as moist pet food, semi-moist pet food, or dry pet food, such as kibbles.
[0048] Generally, the medium chain triglycerides can be about 0.5% to about 60% by weight of the composition. In one aspect, the medium chain triglycerides can be from about 1% to about 20% by weight of the composition. In other aspects, the medium chain triglyce...
Embodiment 1
[0065] Example 1-Heart health mixed study on canines with DMVD
[0066] 19 healthy dogs and 21 dogs with heart murmurs were selected for a 6-month study. All dogs were examined by a professionally certified veterinary cardiologist using echocardiography and were confirmed to be healthy or suffering from early degenerative mitral valve disease (DMVD). The dogs in each group were randomly divided into two diet treatment groups according to age, sex, breed, weight and murmur level. The control diet manufactured by Nestle Purina PetCare Company provides complete and balanced nutrition to meet or exceed the requirements set by the American Association of Feed Control Officials (AAFCO). The test diet contains all the ingredients in the control diet and the following additional ingredients: medium chain triglycerides (MCT) in an amount of 5.000% by weight, omega-3 fatty acids in an amount of 0.7489% by weight, lysine in an amount of 2.3000% by weight, Methionine and cysteine in an ...
Embodiment 2
[0071] Example 2-Heart health mixed study on canines with DMVD
[0072] Seven beagle dogs and one miniature Scherena were selected for the study. All dogs were examined by a professionally certified veterinary cardiologist using echocardiography and were classified as suffering from degenerative mitral valve disease (DMVD). The dogs were randomly assigned to two diet treatment groups. The control diet manufactured by Nestle Purina PetCare Company provides complete and balanced nutrition to meet or exceed the requirements set by the American Association of Feed Control Officials (AAFCO). The test diet contains the same ingredients as the control diet, except that it additionally contains 7% medium chain triglycerides (MCT). The diet is isocaloric and contains the same amount of nitrogen. The diet is shown in Table 1.
[0073] Table 1
[0074] Ingredients / nutrients
Control diet
Test diet
Medium chain triglycerides (MCT),%
0.0
7.0
Omega-3 fatty acids,%
0.8
0.8
Lysine,%
2....
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