Centrifugal micro-fluidic splitter

Abstract

The invention provides a centrifugal micro-fluidic splitter. The centrifugal micro-fluidic splitter comprises a centrifugal driving mechanism, a plurality of connection pieces and a plurality of detection card boxes; the centrifugal driving mechanism is provided with a centrifugal rotary shaft; the first ends of the connection pieces are connected with the centrifugal rotary shaft; the detection card boxes comprise box bodies, box covers, photoelectric sensors and temperature control modules, the box bodies are provided with cavity structures with one ends being open, the photoelectric sensorsand the temperature control modules are all arranged on the side walls of the corresponding cavity structures, micro-fluidic chips are located in the cavity structures of the box bodies, and the photoelectric sensors align the detection cavities of the micro-fluidic chips. The micro-fluidic splitter is characterized in that the capacity of the cavity structures of the box bodies is smaller, the temperature control modules can control the temperature more precisely and are particularly suitable for biochemical reactions which are sensitive to temperature reactions, and accordingly the detection results are more precise. Due to the positions of the photoelectric sensors and the micro-fluidic chips are relative still, accordingly the photoelectric sensors can detect the photoelectric signalsof the detection cavities of the micro-fluidic chips.

Description

technical field [0001] The invention relates to the field of microfluidic technology, in particular to a centrifugal microfluidic device. Background technique [0002] Microfluidics refers to the manipulation of liquids on the submillimeter scale, generally in the range of a few microns to hundreds of microns. Microfluidics integrates the basic operating units involved in the fields of biology and chemistry, and even the entire assay operation, including sampling, dilution, reaction, separation, detection, etc., on a small chip, so it is also called Lab-on-a-Chip (Lab-on-a-chip). -a-Chip). This kind of chip is generally composed of various liquid storage pools and interconnected microchannel networks, which can greatly shorten the sample processing time, and realize the maximum utilization efficiency of reagent consumables through precise control of liquid flow. Microfluidics provides extremely broad prospects for applications in many fields such as biomedical research, dr...

AI Technical Summary

Problems solved by technology

In addition, the current centrifugal microfluidics is hardly capable of real-time reading of the signal of the detection chamber in the disc chip in the high-speed centrifugal state.

[0006] In traditional centrifugal microfluidics, in order to avoid serial contamination of different samples in the subsequent liquid manipulation, a single disc chip can often only process a single sample

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