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Neutron capture treatment system based on proton linear accelerator

A linear accelerator and treatment system technology, applied in the field of neutron capture treatment system, can solve the problems of increasing hospital equipment investment cost, unable to meet hospital use requirements, and expanding land use requirements

Pending Publication Date: 2018-12-21
国科中子医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hospitals that introduce PET usually build an independent PET center to accommodate the radioisotope production system based on low-energy proton accelerators, which greatly increases the hospital’s equipment investment costs and expands the need for additional land, which cannot meet the needs of most hospitals. Requirements

Method used

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  • Neutron capture treatment system based on proton linear accelerator
  • Neutron capture treatment system based on proton linear accelerator
  • Neutron capture treatment system based on proton linear accelerator

Examples

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Effect test

Embodiment 1

[0064] A neutron capture therapy system based on a high-current proton linear accelerator, such as figure 1 As shown, it includes: a proton generation section 100, a proton acceleration section 200, a proton application section 300 and a control system 400; the proton generation section 100, the proton acceleration section 200, and the proton application section 300 are connected in sequence, and the control The system 400 is electrically connected with the proton generation section 100 , the proton acceleration section 200 , and the proton application section 300 respectively.

[0065]Wherein, the proton generating section 100 is used to generate high-current proton beams. In this embodiment, the proton generating section 100 can adopt an electron cyclotron resonance (ECR) proton generating section or a Penning source, and the generated ions are preferably protons. In some other embodiments, the ions can also be For other ions, the ion exit energy is tens of kiloelectron vol...

Embodiment 2

[0075] It is a further improvement on the basis of Embodiment 1. The difference from Embodiment 1 is that in this embodiment, the proton application section 300 includes a production application system 310 and two neutron capture therapy systems 320, the The two neutron capture therapy systems 320 are respectively a first neutron capture therapy system and a second neutron capture therapy system.

[0076] Specifically, when performing BNCT treatment, a first patient is assigned in the first neutron capture therapy system, and when ready, the beam is directed to the first neutron capture therapy system by using the beam switching system 223, and the first patient Accept neutron irradiation; during the treatment of the first neutron capture therapy system, the second patient can be assigned to the second neutron capture therapy system and make preparations. After the irradiation treatment of the first neutron capture therapy system is completed, the second patient After the neut...

Embodiment 3

[0079] The difference between this embodiment and Embodiment 1 is that in this embodiment, the proton application section 300 includes a production application system 310 and two neutron capture therapy systems 320, and the two neutron capture therapy systems 320 They are respectively the first neutron capture therapy system and the second neutron capture therapy system. The irradiation direction of the first neutron capture therapy system is along the vertical direction, and the second neutron capture therapy system can rotate around the patient at a certain angle during treatment, and its irradiation direction can be adjusted according to the rotation angle.

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Abstract

The invention discloses a neutron capture treatment system based on a proton linear accelerator. The neutron capture treatment system comprises a proton generating section for generating a high current proton beam, a proton acceleration section for accelerating and transporting the proton beam, a proton application section, and a control system. The proton application section includes a productionapplication system and a neutron capture treatment system; the production application system is used for producing and extracting radionuclide; and the neutron capture treatment system is used for external irradiation of a body tumor. The control system is in electrical signal connection with the proton generating section, the proton acceleration section, and the proton application section respectively. The neutron capture treatment system having advantages of compact structure, high integration, small size, great convenience of installation and reduced cost can be arranged in the existing hospital and has the BNCT treatment function and the radioisotope production function.

Description

technical field [0001] The invention belongs to the field of medical technology, in particular to a neutron capture therapy system based on a proton linear accelerator. Background technique [0002] Boron Neutron Capture Therapy (BNCT) is a bio-targeted binary radiotherapy mode with "drug-machine combination" and better safety. It has the advantages of radiotherapy, chemotherapy, heavy ion therapy and other means in principle Advantages, the most hopeful realization of human good wishes to cure tumors. BNCT treatment first injects non-toxic boron-carrying drugs with pro-tumor tissue into human blood, and after the boron (boron-10) drugs are enriched in tumor tissues, epithermal neutrons are used to irradiate the tumor site in a multi-directional conformal manner. When the protons meet the boron-10 nuclides in cancer cells and undergo a nuclear reaction, the released alpha particles and lithium-7 particles have strong lethality to cells, and the killing effect is higher than...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/10H05H3/06H05H7/22
CPCA61N5/1001A61N5/1064H05H3/06H05H7/22A61N2005/1094A61N2005/109A61N2005/1087H05H2277/11
Inventor 陈朝斌张熹寅刘贵议黄红李国威乔磊李建霖
Owner 国科中子医疗科技有限公司
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