Compound oligopeptide capable of improving sexual functions and resisting fatigue, oral preparation of compound oligopeptide and preparation method of oral preparation

A technology of oral preparations and oligopeptides, which is applied in the field of compound oligopeptides, its oral preparations and the preparation of the oral preparations, and can solve problems such as unclear side effects and safety considerations

Active Publication Date: 2018-12-18
河南东肽生物有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the formula of the published patent contains yam, the main ingredient is still Chinese herbal medicine. The safety needs to be considered, and the side effects that may be brought to the human body after long-term use are not clear

Method used

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  • Compound oligopeptide capable of improving sexual functions and resisting fatigue, oral preparation of compound oligopeptide and preparation method of oral preparation
  • Compound oligopeptide capable of improving sexual functions and resisting fatigue, oral preparation of compound oligopeptide and preparation method of oral preparation
  • Compound oligopeptide capable of improving sexual functions and resisting fatigue, oral preparation of compound oligopeptide and preparation method of oral preparation

Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment 1

[0069] (1) Shelling and beating: take fresh oysters, shell them to get oyster meat, add water, the mass ratio of water to oyster meat is 1:1, and beat into a slurry;

[0070](2) Enzymolysis treatment: adopt biological enzymolysis technology to carry out enzymolysis treatment to the slurry obtained in step (1), the enzyme used is alkaline protease (2.4AU / g, Novozymes, Denmark), and the amount of enzyme added is 1 / 2 of the oyster slurry quality. 2%, the enzymolysis temperature is 50°C, the pH is 8, and the enzymolysis time is 6 hours, the enzymolysis solution is obtained, and the degree of hydrolysis is 20.3%;

[0071] (3) Enzyme-inactivating treatment: the enzymatic hydrolyzate obtained in step (2) was subjected to boiling water to inactivate the enzyme for 10 minutes;

[0072] (4) Clarification treatment: the enzymolysis solution after step (3) deenzyme treatment adopts centrifugation to get the supernatant for subsequent use, centrifugation adopts 10000r / min, centrifugation 1...

preparation Embodiment 2

[0084] (1) Shelling and beating: take fresh oysters, shell them to get oyster meat, add water, the mass ratio of water and oyster meat is: 2:1, and beat into a slurry;

[0085] (2) Enzymolysis treatment: adopt biological enzymolysis technology to carry out enzymolysis treatment to the slurry obtained in step (1), the enzyme used is selected neutral protease (0.8AU / g, Novozymes, Denmark), and the amount of enzyme added is 1 / 2 of the substrate mass. 2%, the enzymolysis temperature is 40°C, the pH is 7, and the time is 8h, the enzymolysis solution is obtained, and the degree of hydrolysis is 19.4%;

[0086] (3) Enzyme-inactivating treatment: the enzymatic hydrolyzate obtained in step (2) was subjected to boiling water to inactivate the enzyme for 10 minutes;

[0087] (4) Clarification treatment: the enzymolyzed solution after step (3) deenzyme treatment adopts centrifugation to get the supernatant for later use, centrifugation adopts 15000r / min, and centrifuges for 10min;

[008...

preparation Embodiment 3

[0097] (1) Shelling and beating: take fresh oysters, shell them to get oyster meat, add water, the mass ratio of water and oyster meat is: 5:1, and beat into a slurry;

[0098] (2) Enzymolysis treatment: adopt biological enzymolysis technology to carry out enzymolysis treatment to the slurry obtained in step (1), the enzyme used is trypsin (1250USP / mg, Novozymes, Denmark), and the amount of enzyme added is 3% of the substrate mass , the enzymolysis temperature is 50°C, the pH is 7, and the time is 10 hours, the enzymolysis solution is obtained, and the degree of hydrolysis is 40.0%;

[0099] (3) Enzyme-inactivating treatment: the enzymatic hydrolyzate obtained in step (2) was subjected to boiling water to inactivate the enzyme for 10 minutes;

[0100] (4) Clarification treatment: the enzymolysis solution after step (3) deenzyme treatment adopts centrifugation to get the supernatant for subsequent use, centrifugation adopts 15000r / min, centrifugation 20min;

[0101] (5) separa...

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Abstract

The invention provides compound oligopeptide capable of improving sexual functions and resisting fatigue, an oral preparation of the compound oligopeptide and a preparation method of the oral preparation to overcome the defects of Chinese herbal medicines in improvement of the sexual function in the prior art. The compound oligopeptide is prepared from main raw materials including oyster oligopeptide and walnut oligopeptide and Chinese yam polysaccharide used as an auxiliary material. The compound oligopeptide is prepared from main raw materials including oyster oligopeptide and walnut oligopeptide which are extracted from purely natural and edible biomaterials and the Chinese yam polysaccharide used as the auxiliary material, the oral preparation in different dosage forms is prepared fordifferent application conditions, and the oral preparation can effectively relieve fatigue and improve the sexual functions.

Description

technical field [0001] The invention belongs to the technical field of male sexual function health care products, and in particular relates to a compound oligopeptide for improving sexual function, its oral preparation and a preparation method of the oral preparation. Background technique [0002] Sexual dysfunction is a common multiple disease that directly affects the mental health of men, damages the relationship between husband and wife, and endangers social stability. In addition, it is closely related to the formation of diabetes, liver and kidney diseases, cardiovascular diseases, prostate diseases, and mental diseases. connect. Sexual dysfunction often makes men have a sense of frustration or self-denial, which damages the relationship between husband and wife and family stability, thereby affecting social function. Therefore, how to effectively improve male sexual dysfunction has become an urgent medical problem in today's society, and because clinical drugs have d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/18A23L33/125A23J1/04A23J3/04A23P10/30A23L2/39A23L5/20
CPCA23J1/006A23J1/04A23J3/04A23L2/39A23L5/20A23L33/125A23L33/18A23P10/30A23V2002/00A23V2200/30A23V2250/55
Inventor 李勇樊蕊
Owner 河南东肽生物有限公司
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