Piezoelectric ultrasonic microinjector

Abstract

The invention discloses a piezoelectric ultrasonic microinjector which comprises a substrate, a screw cap and a piezoelectric ceramic vibrating module fixedly mounted at two ends of the substrate, anend cover fixed to the screw cap, bent plain end injection needles fixedly mounted on the screw cap and the end cover and a fixed bar fixedly mounted on the piezoelectric ceramic vibrating module. Thepiezoelectric ultrasonic microinjector disclosed by the invention is simple in structure, good in interchangeability of parts, easy to process and relatively low in processing cost, and the experimental cost of a microinjection experimental operation is lowered and the complex degree of the microinjection experimental operation is simplified.

Description

technical field [0001] The invention relates to the technical field of microinjection equipment, in particular to a piezoelectric ultrasonic microinjector. Background technique [0002] With the development of modern bioengineering technology in the 21st century, human beings have a better understanding and understanding of tiny cells. Many of the cognition and analysis of major diseases or genetic symptoms originate from cells or even more microscopic living individuals. However, the difficulty in observing, analyzing and manipulating human tissues, cells or genetic material has always been a problem hindering the development of bioengineering. The cell membrane rupture and puncture itself are achieved by directly destroying the cell tissue. In addition, the cell scale is very small, and the lack of feedback on the early stage of the operation or real-time mechanical information makes it difficult to control the damage to the cells during the operation. The attenuation of ...

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Problems solved by technology

However, the difficulty in observing, analyzing and manipulating human tissues, cells or genetic material has always been a problem hindering the development of bioengineering

The cell membrane rupture and puncture itself are achieved by directly destroying the cell tissue. In addition, the cell scale is very small, and the early stage of the operation process or the lack of real-time mechanical information feedback make it difficult to control the damage to the cells during the operation. The attenuation of damage during cell injection has always been a core issue for all researchers

However, the design of the existing cell injector easily leads to radial movement of the injection microneedle at the front end under excitation, so that the injection will cause mechanical damage to the cells, inactivate the cells during the injection process, and reduce the success rate of the experiment.

Finally, existing piezoelectric ultrasonic microinjectors cannot be used with curved microneedles used in conventional laboratories for cell manipulation experiments

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