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A quick-loading leak-proof microfluidic chip

An anti-leakage, chip technology, applied in the field of cell culture, can solve the problems of inconvenient installation, liquid leakage, inconvenient cultivation, etc., and achieve the effects of fast and convenient installation, leakage prevention and reasonable design

Active Publication Date: 2020-01-07
WUHAN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the microfluidic chips currently on the market have complex structures and cumbersome manufacturing processes, which often bring large manufacturing costs during the manufacturing process, and are inconvenient to install after manufacturing, and traditional microfluidic chips are prone to liquid leakage. Disadvantages, leading to infection of cells, inconvenient cultivation, and imperfect treatment of waste liquid, and the existing microfluidic chip is inconvenient to control the temperature during the reaction detection process

Method used

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  • A quick-loading leak-proof microfluidic chip
  • A quick-loading leak-proof microfluidic chip
  • A quick-loading leak-proof microfluidic chip

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Embodiment Construction

[0022] Below by embodiment, in conjunction with accompanying drawing, the technical scheme of the present invention is described further specifically, as Figure 1-4 As shown, a quick-install leak-proof microfluidic chip includes a substrate 3, a culture plate 4 and a cover plate 6 arranged sequentially from bottom to top, and the four corners of the surfaces of the substrate 3, culture plate 4 and cover plate 6 are Any three corners are provided with positioning holes 2, and the four corners of the surface of the substrate 3, the culture plate 4 and the cover plate 6 are provided with the positioning holes 2, and the remaining corner is provided with an offset hole 7, and the cover plate The center of the upper surface of 6 is provided with a waste liquid storage hole 9, and the inside of the cover plate 6 is provided with a drain hole 5 communicating with the waste liquid storage hole 9, and the two sides of the waste liquid storage hole 9 are provided with There is a liquid...

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Abstract

The invention discloses a fast-assembly anti-leakage microfluidic chip, comprising a base plate, a culture plate and a cover plate, wherein the base plate, the culture plate and the cover plate are separately provided with an offset hole and locating holes; a waste liquid storage hole is formed in the middle of the cover plate; the cover plate is internally provided with a liquid discharge hole communicated with the waste liquid storage hole; liquid injection holes are respectively formed at the two sides of the waste liquid storage hole; a filter slot is formed between each liquid injection hole and the waste liquid storage hole; a first adhesion layer and a second adhesion layer are respectively arranged on the upper and low side faces of the culture plate. The fast-assembly anti-leakagemicrofluidic chip is reasonable in design and convenient to use; a unidirectional permeable membrane is arranged, so that waste liquid and culture liquid can be effectively separated from each other;the liquid injection holes and the liquid storage hole are reasonably designed, so that the culture liquid is prevented from leaking, and the disadvantage of liquid leakage between gaps is further avoided; the overall temperature of the microfluidic chip can be also adjusted with one button, so that a suitable temperature environment is provided for reaction and detection; the fast-assembly anti-leakage microfluidic chip is practical in functions and suitable for wide application.

Description

technical field [0001] The invention relates to the technical field of cell culture, in particular to a quick-package leak-proof microfluidic chip. Background technique [0002] Microfluidic chip technology integrates the basic operation units of sample preparation, reaction, separation, and detection in the process of biological, chemical, and medical analysis into a micron-scale chip, and automatically completes the entire analysis system. Due to its great potential in the fields of biology, chemistry, and medicine, it has developed into a new research field interdisciplinary with biology, chemistry, medicine, fluid, electronics, materials, and mechanics. [0003] However, the microfluidic chips currently on the market have complex structures and cumbersome manufacturing processes, which often bring large manufacturing costs during the manufacturing process, and are inconvenient to install after manufacturing, and traditional microfluidic chips are prone to liquid leakage....

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01L3/00
CPCB01L3/5027B01L3/502753B01L2200/141B01L2300/1827
Inventor 李捷叶健陈钧剑靳浩陈海文
Owner WUHAN UNIV OF TECH
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