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A kind of traditional Chinese medicine compound prescription for preventing and treating livestock and poultry diarrhea and its preparation process

A preparation process and a technology for livestock and poultry diarrhea, applied in the field of traditional Chinese veterinary medicine, can solve problems such as large water content of medicinal residues, and achieve the effects of fast disappearance of symptoms, rapid effect and reliable curative effect.

Active Publication Date: 2021-05-28
NANJING AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The extracted medicinal dregs have a large water content and are generally treated as solid waste, which brings certain pressure to environmental protection

Method used

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  • A kind of traditional Chinese medicine compound prescription for preventing and treating livestock and poultry diarrhea and its preparation process
  • A kind of traditional Chinese medicine compound prescription for preventing and treating livestock and poultry diarrhea and its preparation process
  • A kind of traditional Chinese medicine compound prescription for preventing and treating livestock and poultry diarrhea and its preparation process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Weigh 26 parts of dandelion, 20 parts of Smilax cocos, 26 parts of Viola chinensis, 20 parts of wild chrysanthemum, and 26 parts of Patrinia according to parts by weight, screen and clean; ultrafinely pulverize the above-mentioned raw materials, and pulverize them to 800-1000 mesh; Add sodium hydroxide and water 80 DEG C and soak for 60 minutes, the extraction solvent is drinking water, the solvent used and the raw material ratio are 6: 1, and the sodium hydroxide addition is solvent 1%; Use decanter centrifuge (3000r / min) and Butterfly centrifuge (6000r / mim) for solid-liquid separation; use dilute hydrochloric acid to adjust the pH value of the extract to the range of 3.5-4.0; concentrate the above extract to a density of 1.05-1.10. The concentration method adopts a three-effect concentrator, and the vacuum degree and evaporation temperature of each effect are: the vacuum degree and evaporation temperature of each effect are: the first effect -0.04~-0.07MPa, 85°C; the s...

Embodiment 2

[0023] Weigh 30 parts of dandelion, 24 parts of Smilax cocos, 30 parts of Viola chinensis, 24 parts of wild chrysanthemum, and 30 parts of Patrinia according to parts by weight, screen and clean; ultrafinely pulverize the above-mentioned raw materials, and pulverize them to 800-1000 mesh; Add sodium hydroxide and water 80 DEG C and soak for 60 minutes, the extraction solvent is drinking water, the solvent used and the raw material ratio are 6: 1, and the sodium hydroxide addition is solvent 1%; Use decanter centrifuge (3000r / min) and Butterfly centrifuge (6000r / mim) for solid-liquid separation; use dilute hydrochloric acid to adjust the pH value of the extract to the range of 3.5-4.0; concentrate the above extract to a density of 1.05-1.10. The concentration method adopts a three-effect concentrator, and the vacuum degree and evaporation temperature of each effect are: the vacuum degree and evaporation temperature of each effect are: the first effect -0.04~-0.07MPa, 85°C; the s...

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Abstract

The invention relates to a compound traditional Chinese medicine for preventing and treating livestock and poultry diarrhea and a preparation process thereof, which is prepared by the following components in parts by weight: 25-30 parts of dandelion, 20-25 parts of Smilax smilax, 25-30 parts of Viola chinensis, 20‑25 parts of wild chrysanthemum, 25‑30 parts of Patrinia. Its preparation method is as follows: each raw material is weighed according to the above-mentioned parts by weight, screened, and the above-mentioned original ultra-fine frozen powder is crushed to 800‑1000 mesh; 1% sodium hydroxide and water are added and soaked at 80 ° C for 60 minutes, respectively Use a decanter centrifuge and a butterfly centrifuge for solid-liquid separation, and use dilute hydrochloric acid to adjust the pH value of the extract to a range of 3.5-4.0. Concentrate the above extract with a three-effect concentrator to a density of 1.05-1.10, filter it centrifugally, spray the concentrated solution to a water-soluble product or absorb it through granular silica, and dry it into a granular powder by paddle screw drying . The invention has heat-clearing, detoxifying and anti-inflammation effects, can have obvious inhibitory effect on Escherichia coli, a common pathogenic bacteria in pigs and chickens, and can replace antibiotics to prevent and treat livestock and poultry diarrhea.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese veterinary medicines, in particular to traditional Chinese medicine prescriptions such as dandelion, smilax smilax, zihuadiding, wild chrysanthemum, Patrinia and the extraction and preparation process. Background technique [0002] Livestock and poultry diarrhea diseases are not only one of the serious problems that plague the farmers in our country, but also one of the main reasons for the loss of animal husbandry in all countries in the world. Antibiotics are the most common way to prevent livestock and poultry diarrhea, but long-term non-standardization and abuse of antibiotics have caused serious drug resistance in pathogens, and drug residues continue to threaten the lives of humans and animals and damage the ecological environment. Therefore, there is an urgent need to study new drugs or technologies to replace antibiotics and reduce their adverse consequences and harms. Traditi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K36/90A61P1/12A61P31/04
CPCA61K36/287A61K36/288A61K36/84A61K36/86A61K36/896A61K36/90A61K2236/331A61K2236/51A61P1/12A61P31/04A61K2300/00
Inventor 王德云朱少武武志勇刘振广胡元亮刘家国
Owner NANJING AGRICULTURAL UNIVERSITY
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