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Externally-applied traditional Chinese medicine composition for relieving eye fatigue, and preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for eyes, can solve the problems of slow eye fatigue alleviation effect, inability to achieve quick effect and the like, and achieve excellent moisturizing effect, eye fatigue alleviation, and muscle tension alleviation effects.

Inactive Publication Date: 2018-10-23
浙江植萃堂生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, the traditional Chinese medicine preparations reported in various patent documents for relieving fatigue symptoms are mainly composed of Chinese medicinal materials and vitamins, and most of them are mainly taken orally. Therefore, the effect of relieving eye fatigue is slow, and it is impossible to achieve a quick effect

Method used

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  • Externally-applied traditional Chinese medicine composition for relieving eye fatigue, and preparation method and application thereof
  • Externally-applied traditional Chinese medicine composition for relieving eye fatigue, and preparation method and application thereof
  • Externally-applied traditional Chinese medicine composition for relieving eye fatigue, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-1

[0065] The dry roots of Ophiopogon japonicus are crushed, passed through a 200-mesh sieve, and 500g is taken, and 60% ethanol solution is added according to the ratio of material to liquid at 1:5, and ultrasonicated in an ultrasonic oscillator (purchased from Shanghai Shengyan Ultrasonic Instrument Co., Ltd. Extract for 20 minutes, the ultrasonic power is 200W, concentrate into an extract, and obtain the ethanol crude extract of Ophiopogon japonicus.

[0066] Macroporous resin AB-8 column, wet packed column, column volume 2L, diameter-to-height ratio 1:8. Disperse the crude extract with a small amount of ethanol to make a loading liquid. They were eluted with 20%, 40%, 60%, and 80% ethanol respectively, and the eluted fractions of 60% and 80% ethanol were collected and dried in vacuum to obtain Ophiopogon japonicus Ext1.

Embodiment 1-2

[0068] The dry roots of Ophiopogon japonicus are crushed, passed through a 200-mesh sieve, and 500g is taken, and 50% ethanol solution is added according to the ratio of material to liquid at 1:8, and ultrasonically ultrasonicated in an ultrasonic oscillator (purchased from Shanghai Shengyan Ultrasonic Instrument Co., Ltd. SCQ-7201C) Extract for 30 minutes, the ultrasonic power is 250W, concentrate into an extract, and obtain the ethanol crude extract of Ophiopogon japonicus.

[0069] Take the macroporous resin AB-8 column, wet pack the column, the column volume is 2L, and the ratio of diameter to height is 1:8. Disperse the crude extract with a small amount of ethanol to make a loading liquid. They were eluted with 20%, 40%, 60%, and 80% ethanol respectively, and the eluted fractions of 60% and 80% ethanol were collected and dried in vacuum to obtain Ophiopogon japonicus Ext2.

Embodiment 1-3

[0071] The dry roots of Ophiopogon japonicus are pulverized, passed through a 200-mesh sieve, and 500 g is taken, and 40% ethanol solution is added according to the ratio of material to liquid at 1:10, and ultrasonically ultrasonicated in an ultrasonic oscillator (purchased from Shanghai Shengyan Ultrasonic Instrument Co., Ltd. Extracted for 40 minutes, the ultrasonic power was 150W, concentrated into an extract, and the ethanol crude extract of Ophiopogon japonicus was obtained.

[0072] Take the macroporous resin AB-8 column, wet pack the column, the column volume is 2L, and the ratio of diameter to height is 1:8. Disperse the crude extract with a small amount of ethanol to make a loading liquid. They were eluted with 20%, 40%, 60%, and 80% ethanol respectively, and the eluted fractions of 60% and 80% ethanol were collected and vacuum-dried to obtain Ophiopogon japonicus Ext3.

[0073] 2. Investigation on extraction process of Sophora flavescens

[0074] Sophora flavescens...

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Abstract

The invention discloses an externally-applied traditional Chinese medicine composition for relieving eye fatigue, and a preparation method and an application thereof. The externally-applied traditional Chinese medicine composition for relieving eye fatigue includes a traditional Chinese medicine extract as a main medicine and an auxiliary material; the traditional Chinese medicine extract includesthe components in parts by weight: 1-10 parts of an ophiopogon japonicus root extract, 0.5-5 parts of a radix sophorae extract and 0.5-5 parts of a cactus stem extract; the auxiliary material includes the components in parts by weight: 0.1-10 parts of ectoine, 0.01-10 parts of B vitamins, 1-10 parts of dipotassium glycyrrhizinate, 0.5-20 parts of pantothenol, 0.1-2 parts of carboxymethyl deacetylchitosan, 0.1-5 parts of sodium hyaluronate, 0.5-2.5 parts of taurine, 0.2-2 parts of trehalose, and 1-10 parts of retinyl palmitate.

Description

technical field [0001] The invention relates to a Chinese medicine composition for eyes, in particular to an external Chinese medicine composition for relieving eye fatigue, its preparation method and application. Background technique [0002] In recent years, with the penetration of computers, televisions, mobile phones and other video display terminals into people's daily life, more and more patients with eye fatigue have become one of the common diseases in ophthalmology. Eye fatigue is a syndrome mainly manifested by subjective symptoms of the eyes. It usually occurs after excessive staring. The main symptoms are: discomfort or pain around the eyeballs and orbits, blurred vision, dry eyes, tearing and other symptoms. In severe cases, nausea, vomiting, dizziness, night sweats, pale complexion, tachycardia, neck muscle tension, shoulder pain and other systemic symptoms may appear, often accompanied by mental symptoms such as listlessness, lethargy, memory loss, and insomni...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P27/02A61K8/9789A61K8/9794A61K8/67A61K8/36A61K8/63A61K8/41A61K8/49A61K8/73A61K8/37A61Q19/00
CPCA61K8/36A61K8/37A61K8/41A61K8/4953A61K8/63A61K8/673A61K8/733A61K8/735A61K8/736A61K8/9789A61K8/9794A61K9/0014A61K36/33A61K36/489A61K36/8968A61K2800/805A61P27/02A61Q19/00A61K2300/00
Inventor 王永兵刘越平任增良
Owner 浙江植萃堂生物科技有限公司
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