A space cell biomechanics experiment system

An experimental system, biomechanical technology, applied in the fields of biochemical cleaning devices, biochemical equipment and methods, enzymology/microbiology devices, etc., which can solve problems such as high reliability requirements and high costs

Active Publication Date: 2021-01-01
INST OF MECHANICS CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In addition, space experiments that are expensive and have few opportunities have high requirements on the reliability of the equipment, so it is necessary to simplify the complexity of the experimental system as much as possible and improve the reliability while meeting the experimental requirements.

Method used

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  • A space cell biomechanics experiment system
  • A space cell biomechanics experiment system
  • A space cell biomechanics experiment system

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Experimental program
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Embodiment Construction

[0032] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments It is a part of embodiments of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0033] In order to facilitate the understanding of the embodiments of the present invention, further explanations will be given below with specific embodiments in conjunction with the accompanying drawings, which are not intended to limit the embodiments of the present invention.

[0034] figure 1 A schematic structural diagram of a space ce...

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Abstract

The embodiment of the invention provides a spatial cell biomechanical experiment system which comprises a first multi-channel pinch valve (1), a second multi-channel pinch valve (2), a first micro peristaltic pump (3), a second micro peristaltic pump (4), a bubble entrapment and gas exchange unit (5) and a culture device (6). The experiment system specifies and quantifies a mechanical microenvironment of a spatial cell culture experiment by means of flow shear control, bubble isolation, culture device substrate modification and the like, and achieves the purpose of analyzing the influence of changes of a gravity condition and other mechanical conditions on cell functions through mechanical microenvironment interference prevention measures. In addition, a liquid circuit of the experiment system is totally-enclosed; overall high-pressure sterilization can be performed to avoid contamination and facilitate full automatic liquid change, circulation, fixing operation and in-situ on-line microscopic observation in an experiment process; and therefore, the experiment system is applicable to a cell biomechanical experiment study under a spatial micro-gravity condition.

Description

technical field [0001] The embodiments of the present invention relate to the field of biotechnology, in particular to a space cell biomechanics experiment system. Background technique [0002] In the study of space cell microgravity effects, changes in gravity conditions are often affected by other mechanical or physical conditions. In order to analyze the impact of changes in gravity and other mechanical conditions on cells, it is necessary to standardize and quantify the mechanical microenvironment of cell growth. . Cell culture in space microgravity faces a series of special problems that are completely different from those on the ground, and the change of fluid behavior caused by the weightless environment also makes the conventional cell culture methods and operations on the ground basically invalid. In ground cell culture, the culture medium is generally static, and natural convection caused by gravity can promote material exchange. Cell culture in space decreases th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M3/00C12M1/36C12M1/00
CPCC12M41/00C12M41/34C12M41/48
Inventor 孙树津王成之陈勤龙勉
Owner INST OF MECHANICS CHINESE ACAD OF SCI
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