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System for determining postoperative recurrent risk of single HBV related primary liver carcinoma within 1 year

A primary, risky technology used in medicine

Active Publication Date: 2018-09-21
BEIJING DITAN HOSPITAL CAPITAL MEDICAL UNIV
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Problems solved by technology

[0005] Current studies mostly focus on the effects of surgical methods, tumor location, and tumor pathological features on the postoperative recurrence rate of patients with small HCC, and there is still a lack of a simple, rapid and effective way to determine the postoperative recurrence rate of single HBV-related primary small HCC. Approach to recurrence risk within 1 year

Method used

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  • System for determining postoperative recurrent risk of single HBV related primary liver carcinoma within 1 year
  • System for determining postoperative recurrent risk of single HBV related primary liver carcinoma within 1 year
  • System for determining postoperative recurrent risk of single HBV related primary liver carcinoma within 1 year

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Embodiment 1

[0028] A retrospective collection of 203 patients with single HBV-related primary small liver cancer from January 2012 to December 2014 in Beijing Ditan Hospital Affiliated to Capital Medical University was collected. The clinical information of the patients was collected, and the age, gender, biochemical indicators, The 1-year cumulative recurrence rate was descriptively analyzed, and the independent risk factors affecting recurrence within 1 year were screened out by COX univariate and multivariate analysis, and a COX proportional hazard regression model was established.

[0029] Diagnostic criteria include:

[0030] Diagnostic criteria for small liver cancer: According to the "Code for Diagnosis and Treatment of Primary Liver Cancer (2011 Edition)" formulated by the Ministry of Health, the diagnostic criteria for small liver cancer are: the largest diameter of a single cancerous nodule ≤ 3cm, and the number of multiple cancerous nodules does not exceed 2, the sum of their l...

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Abstract

The present invention provides a system for determining a postoperative recurrent risk of a single HBV related primary liver carcinoma within 1 year. The system comprises an input device, a computingdevice and an output device, the computing device comprises a storage and a processor, a computer program is stored in the storage, the processor is configured to execute the computer program stored in the storage to achieve an algorithm of a discrimination function. The discrimination function returns the postoperative recurrent risk of the single HBV related primary liver carcinoma within 1 yearthrough the history of drinking, glutamyl transpeptidase (GGT), total serum protein content (TP) and alpha fetoprotein (AFP). Through baseline clinical features of biochemistry, virology and immunology, the system provided by the invention can determine the postoperative recurrent risk of the single HBV related primary liver carcinoma within 1 year and provides basis for clinical prognosis.

Description

technical field [0001] The present disclosure relates to the field of medicine, and in particular, relates to a system for determining the risk of recurrence within one year after operation of single HBV-related primary small liver cancer. Background technique [0002] Primary liver cancer is one of the most common malignant tumors in my country. According to the latest data in 2015 from "Global Cancer Report", there were 782,500 new liver cancer patients worldwide in 2012 (ranking the sixth in cancer incidence), and 745,500 patients died (ranking in cancer incidence). The second place in death), among which the proportion of new cases and deaths of liver cancer in my country is quite high, reaching more than 50% of the global total. Therefore, the treatment of primary liver cancer and the postoperative recurrence rate and survival rate are the focus and top priority of researchers. [0003] With the continuous improvement of imaging technology, the detection rate of small l...

Claims

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Application Information

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IPC IPC(8): G16H50/30
CPCG16H50/30
Inventor 杨志云何玲玲刘晓利王宪波江宇泳周桂琴王晓静
Owner BEIJING DITAN HOSPITAL CAPITAL MEDICAL UNIV
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