Application of PI3K (Phosphatidylinositol 3-Kinase) inhibitor to preparation of medicine for treating related diseases of thrombocytopenia
A technique for thrombocytopenia and platelets, which is used in the field of PI3K inhibitors to prepare medicines for diseases related to decreased platelet counts, and can solve problems such as shortening the lifespan of platelets
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[0033] 1. Experimental mice
[0034] All experimental animal-related welfare is strictly implemented in accordance with the "Regulations on the Administration of Experimental Animals" of the People's Republic of China. Animal experiments were approved by the Medical Ethics Committee of Soochow University.
[0035] 2. Wash platelets
[0036] Healthy adult volunteers collected blood from the median vein of the elbow. Blood donors have no bad living habits such as smoking and drinking, and have not taken any drugs that affect platelet function within 2 weeks before blood donation. Female blood donors are not menstruating. All blood donors gave informed consent and signed the agreement. The experimental protocol was approved by the Ethics Committee of the First Affiliated Hospital of Soochow University and complied with the Declaration of Helsinki.
[0037]A certain amount of venous blood was drawn from a healthy person and anticoagulated with 1 / 7 volume of Acid-citratedextro...
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