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Application of Leucojum vernum aqueous extract in regulation of fibroblast cell cycle

A fibroblast, cell cycle technology, applied in cosmetic preparations, skin care preparations, pharmaceutical formulas, etc., can solve the problem of large research space for snow lotus water extracts

Active Publication Date: 2018-07-20
JALA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

There is still a lot of room for research on the water extract of snowflakes

Method used

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  • Application of Leucojum vernum aqueous extract in regulation of fibroblast cell cycle
  • Application of Leucojum vernum aqueous extract in regulation of fibroblast cell cycle
  • Application of Leucojum vernum aqueous extract in regulation of fibroblast cell cycle

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Embodiment Construction

[0025] The present invention is further illustrated below by means of examples, but the present invention is not limited to the scope of the examples. For the experimental methods that do not specify specific conditions in the following examples, select according to conventional methods and conditions, or according to the product instructions.

[0026] In the present invention, during the culture process of fibroblasts, the water extract of Leucorrhizae is added to measure its cell cycle, and then the water extract of Leucojum is removed from normal culture, and the cell cycle and cell activity are continuously measured to observe whether the cells are damaged. If the number of cells in the G1 phase of the cell cycle is increased under the condition of ensuring normal cell activity, it can effectively reflect the effect of the water extract of Snowflake Lotus on regulating the fibroblast cell cycle.

[0027] 1. Preparation of the water extract of Snow Lotus

[0028] Wash and ...

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Abstract

The invention discloses an application of a Leucojum vernum aqueous extract in the regulation of the fibroblast cell cycle. The Leucojum vernum aqueous extract can regulate the fibroblast cell cycle to increase the number of fibroblast cells in the G1 cell cycle by 3.72-31.44%, so the application fills in the gap in the fibroblast cell cycle regulation of the Leucojum vernum aqueous extract in theprior art.

Description

technical field [0001] The present invention relates to the application of snowflake lotus water extract in regulating fibroblast cell cycle. Background technique [0002] In the production of cosmetics, anti-aging cosmetics have always been concerned by people, because the problem of resisting skin aging is the focus of public attention. Protecting the skin and delaying skin aging is the dream of many people, so the development and application of anti-aging cosmetics is an important research direction in the cosmetics industry. [0003] The aging of the skin surface is reflected at the cellular level as cellular aging. In aging skin, there is weakened cell proliferation caused by fibroblast aging, insufficient synthesis or even increased degradation of collagen and other extracellular matrix components, leading to dermal aging. Therefore, it is of far-reaching significance to study how to slow down the aging of fibroblasts and delay skin aging. [0004] Snowdrop (Leucoju...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61Q19/08
CPCA61Q19/08A61K8/97
Inventor 宋肖洁吴越方兆华史晓婷周春霞张佳伟
Owner JALA GROUP CORPORATION
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