Method for solving frequency spectral signal attenuation problem of Fourier transform ion mobility spectrometer

Abstract

The invention discloses a method for solving a frequency spectral signal attenuation problem of a Fourier transform ion mobility spectrometer. The method comprises the steps: in the work process of the Fourier transform ion mobility spectrometer, adjusting a gate closing voltage of an ion gate; under each gate closing voltage in the adjustment process, observing a change condition of a signal meanvalue of frequency spectral signals in the process of increasing the frequency of sweep frequency; and according to the change condition of the signal mean value, selecting the gate closing voltage,having the change amplitude of the signal mean value along with frequency increase less than a preset value, as a best gate closing voltage of the ion gate. The method can improve the frequency spectral signals of the Fourier transform ion mobility spectrometer simply and effectively, improve the quality of the signals and improve the sensitivity and resolution ratio of the detection.

Description

technical field [0001] The invention relates to the field of Fourier transform ion mobility spectrometer, in particular to a method for solving the spectral signal attenuation problem of Fourier transform ion mobility spectrometer. Background technique [0002] Ion mobility spectrometry (IMS) detection technology is an effective chemical substance analysis method, which is sensitive, fast and convenient, and can be widely used in on-site detection. IMS-based detection instruments have been widely used in airports, docks, stations and other places for trace detection of explosives, drugs and other dangerous goods. [0003] Fourier transform ion mobility spectrometry (FT-IMS), as a new type of ion mobility spectrometry, has the characteristics of high sensitivity and high signal-to-noise ratio compared with traditional IMS, and has a good application prospect in trace detection. At present, in the research and application of FT-IMS, there is a common problem that the spectrum...

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Problems solved by technology

[0005] The main purpose of the present invention is to propose a method for solving the spectral signal attenuation problem of the Fourier transform ion mobility spectrometer, and solve the ubiquitous problem in the Fourier transform ion mobility spectrometry detection technology by adjusting the closing voltage of the two ion gates. The problem of spectral signal attenuation as frequency rises to improve the resolution and sensitivity of FT-IMS

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