Microfluidic chip, analysis device and control method of microfluidic chip

Abstract

The invention provides a microfluidic chip, an analysis device, and a control method for the microfluidic chip. The microfluidic chip includes: a plurality of detection electrode groups, and the plurality of detection electrode groups are arranged at intervals along the direction of micro-droplet flow, each Each of the detection electrode groups includes a first detection electrode and a second detection electrode spaced apart from each other, and the first detection electrode and the second detection electrode are used to form a circuit with the micro-droplet to determine the micro-droplet s position. The microfluidic chip can realize the real-time positioning of micro-droplets, and the cost is low, which is conducive to integration and miniaturization. The use of current feedback can avoid the interference of the environment and the biochemical reaction of micro-droplets. No basis can reduce the amount of calculation data, increase reliability, and the applied voltage is low, which will not affect the driving of micro-droplets.

Description

technical field [0001] The invention relates to the field of microfluidic technology, and in particular, to a microfluidic chip, an analysis device and a control method for the microfluidic chip. Background technique [0002] Electrowetting digital microfluidics uses the dielectric wetting effect to achieve separation, directional movement, and mixing of micro-droplets by controlling the voltage of the electrodes. In this method, the flatness of the hydrophobic layer in direct contact with the microdroplets is crucial, which directly affects the transport of the microdroplets. For example, dust, excessive surface roughness and other reasons will affect the flatness of the chip surface, resulting in the failure of the micro-droplets to be transported according to the predetermined timing, resulting in the failure of the reaction. In order to realize the automatic and accurate transportation of micro-droplets, it is necessary to detect the position of micro-droplets in real t...

AI Technical Summary

Problems solved by technology

At present, the visual feedback system is commonly used, but the equipment is expensive, the cost is high, and the amount of data to be processed is huge

[0003] Therefore, the related technologies of existing microfluidic chips still need to be improved.

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