Alcohol-based skin disinfectant with microbicidal properties

Abstract

A skin antiseptic composition comprising fatty alcohol (0.1-90% w / w), chelating agent (0.1-5%), hydrotrope (0.1-5.0%), acid (0.01-5.0%) for pH adjustment 5%), C10 to C16 alkylbenzene sulfonates (0.1‑1.0%), chaotropic agents (0.01‑10%), sesquiterpenoids (0.01‑1%), skin moisturizing, conditioning and / or emollient skin agent (0.01‑10%) and water for balancing. The composition may be liquid, foaming or it may be a thickened gel.

Description

technical field [0001] The present invention relates to alcohol-based formulations for rapid disinfection of the skin. Background technique [0002] The aspect of hand hygiene is very important in the fight against care-associated infections and the spread of pathogens. However, in hospitals, compliance with hand washing with water and soap is not as important as it should be because there are too many restrictions (requiring hand washing, rinsing and drying followed by hand sanitization). This is why some hydroalcoholic formulations have started to be developed in the industry. [0003] These products, which came on the market in the 90's, were first not appreciated by the hygienists who promoted handwashing compliance at the time. Since quite a few studies have demonstrated that the use of mild soap followed by an alcohol-based hand sanitizer reduces the incidence of occupational hand dermatitis. Today, as a supplement to soap, alcohol-based hand sanitizers are the pref...

AI Technical Summary

Problems solved by technology

However, increasing the alcohol concentration above 80% results in a loss of bactericidal efficacy; 20 to 30% water is necessary to allow the alcohol to penetrate the bacterial cell and coagulate its cytoplasmic proteins

Also, high concentrations of alcohol are unsuitable in terms of skin tolerance because of increased transdermal water loss and associated skin dehydration

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