Gynecological lotion containing chitosan quaternary ammonium salt and preparation method of gynecological lotion

A chitosan quaternary ammonium salt, gynecological technology is applied in the field of gynecological lotion containing chitosan quaternary ammonium salt and its preparation field, and can solve the problems of bacteria invading the genitals, unsatisfactory effect, weak antibacterial effect, etc. Prevents skin and mucous membrane infections, is not easily decomposed by bacteria, and has a remarkable antibacterial effect

Inactive Publication Date: 2018-05-29
GUANGZHOU RAINHOME PHARM&TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] People choose to use care solutions containing pure biological formulas, and the irritation is indeed reduced. However, most pure biological preparations themselves have weak antibacterial effects, causing bacterial infections during the manufacturing process, and the bacteria seriously exceed the standard, causing more bacteria to invade the genitals and endanger health.
There are also many nursing solutions containing chlorine in the majority. Chlorine is a strong oxidant, which not only stimulates the skin and hurts the genitals, but also kills most of the beneficial bacteria in the genitals, which makes the flora out of balance, reduces the body's resistance, and causes some Pathogenic bacteria reproduce more
[0005] The effects of various disinfectants in the prior art in terms of treatment and prevention are not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A kind of gynecological lotion containing chitosan quaternary ammonium salt, the gynecological lotion of described chitosan quaternary ammonium salt is made from the following raw materials by weight: 0.01 part of chitosan oligosaccharide, chitosan quaternary ammonium 0.01 part of salt, 0.5 part of aloe extract, 0.5 part of cranberry extract, 0.2 part of natural lactic acid, 0.2 part of DL-pyrrolidone carboxylate sodium solution (PCA-Na), 0.2 part of surfactant, 70 parts of purified water.

[0034] The preparation method of described aloe extract comprises the steps:

[0035] Select mature aloe vera leaves, wash and peel them, beat the aloe vera, add 70% ethanol aqueous solution of 4 times the volume of the aloe vera pulp to extract, the extraction temperature is 40 ° C, the extraction time is 1 h, filter after extraction, obtain a filtrate, and pour into the filter residue Add 70% ethanol aqueous solution which is 3 times its weight in volume and continue to extract fo...

Embodiment 2

[0044] A kind of gynecological lotion containing chitosan quaternary ammonium salt, the gynecological lotion of described chitosan quaternary ammonium salt is made from the following raw materials by weight: 4 parts of chitosan oligosaccharide, chitosan quaternary ammonium 4 parts of salt, 1 part of aloe extract, 1 part of cranberry extract, 1 part of natural lactic acid, 1 part of DL-pyrrolidone carboxylate sodium solution (PCA-Na), 1 part of surfactant, 110 parts of purified water.

[0045] The preparation method of described aloe extract comprises the steps:

[0046] Select mature aloe vera leaves, wash and peel them, beat the aloe vera, add 70% ethanol aqueous solution of 8 times the volume of the aloe vera pulp to extract, the extraction temperature is 60 ° C, the extraction time is 3 hours, filter after extraction, obtain a filtrate, and pour it into the filter residue 70% aqueous ethanol solution of 6 times its weight was added to continue the extraction for 3 hours, th...

Embodiment 3

[0055] A kind of gynecological lotion containing chitosan quaternary ammonium salt, the gynecological lotion of said chitosan quaternary ammonium salt is made from the following raw materials by weight: 0.08-2 parts of chitosan oligosaccharide, chitosan 0.08 part of quaternary ammonium salt, 0.7 part of aloe extract, 0.7 part of cranberry extract, 0.4 part of natural lactic acid, 0.4 part of DL-sodium pyrrolidone carboxylate solution, 0.4 part of surfactant, 80 parts of purified water.

[0056] The preparation method of described aloe extract comprises the steps:

[0057] Select mature aloe vera leaves, wash and peel them, beat the aloe vera, add 70% ethanol aqueous solution of 5 times the volume of the aloe vera pulp for extraction, the extraction temperature is 45 ° C, the extraction time is 1.5 h, filter after extraction, obtain a filtrate, and pour Add 70% ethanol aqueous solution of 4 times its weight to the filter residue and continue to extract for 1.5 hours. The extrac...

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PUM

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Abstract

The invention relates to the field of medicinal products and in particular to a gynecological lotion containing chitosan quaternary ammonium salt and a preparation method of the gynecological lotion,Aiming at defects of the prior art, the invention provides a composite female gynecological lotion, and in particular provides the gynecological lotion containing chitosan quaternary ammonium salt andthe preparation method of the gynecological lotion. The gynecological lotion comprises four main components, namely chitosan, chitosan quaternary ammonium salt, aloe and cranberries. The gynecological lotion has a good synergistic antibacterial effect, is good in antibacterial effect, in addition has certain drug resistance functions and is applicable to popularization and application.

Description

technical field [0001] The invention relates to the field of medical products, in particular to a gynecological lotion containing chitosan quaternary ammonium salt and a preparation method thereof. Background technique [0002] The female genitals are the main organ of metabolism and secretion, and the opening of the vagina is the portal of the two major systems of reproduction and urinary system, so it is very easy to be infected with various diseases. Vaginitis and vulvitis caused by infection of bacteria and viruses can cause genital itching, leucorrhea, condyloma, cervical erosion, etc., which bring unspeakable pain to women. If it is not prevented or treated in time, it will not only affect women Physical and mental health, and will accelerate the aging of sexual organs. [0003] In the prior art, Chinese patent CN102755260B mentions that the cleaning and health care solution utilizing fly maggot chitosan not only has a bactericidal and health care effect, but also can...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K36/886A61P15/02A61P15/00A61K31/722A61K31/702
CPCA61K9/0034A61K31/702A61K31/722A61K36/45A61K36/886A61K36/896A61K47/22A61K2300/00
Inventor 黄海艳车七石
Owner GUANGZHOU RAINHOME PHARM&TECH CO LTD
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