Microwave sterilization process for traditional Chinese medicines

A technology for microwave sterilization and Chinese medicinal materials, applied in irradiation, disinfection and other directions, can solve the problems of loss of volatile components and heat-sensitive components of medicinal materials, poor uniformity of sterilization, and high energy consumption, so as to reduce the loss of effective components of medicines. , the effect of fast speed and low sterilization temperature

Inactive Publication Date: 2018-05-08
CHONGQING HUAAO PHARMA IND CO LTD
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(The other two sterilization methods: ozone sterilization and ethylene oxide sterilization are rarely used because they cannot be used in large-scale production of traditional Chinese medicine)
These sterilization methods have their own disadvantages or imperfections to varying degrees, which will ultimately affect the stability of the product quality of Chinese patent medicines, the strict implementation of GMP standards for drug production, and energy saving and consumption reduction: ① Moist heat steam sterilization, commonly used It is good for the sterilization of raw medicinal materials; however, due to the cold air in the medicinal materials, the steam is not easy to penetrate, and it must reach a certain temperature and maintain a certain period of time to achieve the sterilization effect. On the one hand, high temperature can easily cause volatile components in the medicinal materials and heat-sensitive components are lost in large quantities. On the other hand, when used for sterilization of a large number of Chinese medicinal materials, the energy consumption is large
However, different forms of medicinal materials have different degrees of absorption of microwave energy, resulting in poor sterilization uniformity. In addition, the water content of sterilized materials is only about 10%, so the sterilization effect of ordinary microwave sterilization is poor.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A microwave sterilization process for Chinese medicinal materials, comprising the following steps:

[0016] (1) Pre-treatment: the raw material Sanqi is pre-treated to obtain Sanqi Chinese herbal medicine;

[0017] (2) Pulverization: pulverize the obtained Panax notoginseng Chinese herbal medicine with a pulverizer to particles no larger than 5mm;

[0018] (3) Microwave sterilization: Put the crushed Chinese herbal medicine particles into a microwave sterilization box for sterilization. According to the characteristics of the Sanqi medicinal material, the sterilization temperature is 70°C and the sterilization time is 50 minutes; the sterilized The traditional Chinese medicinal materials enter the next process for standby.

Embodiment 2

[0020] A microwave sterilization process for Chinese medicinal materials, comprising the following steps:

[0021] (1) Pretreatment: the raw material Corydalis Corydalis is pretreated to obtain Corydalis Corydalis Chinese herbal medicine;

[0022] (2) Pulverization: pulverize the obtained Corydalis Chinese herbal medicine with a pulverizer to particles no larger than 5mm;

[0023] (3) Microwave sterilization: Put the pulverized Corydalis Chinese herbal medicine particles into a microwave sterilization box for sterilization. According to the characteristics of the Corydalis Corydalis variety, the sterilization temperature is 60°C and the sterilization time is 60 minutes; the sterilized The traditional Chinese medicinal materials enter the next process for standby.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a microwave sterilization process for traditional Chinese medicines. The microwave sterilization process comprises the following steps: (1) performing pretreatment, namely performing pretreatment on raw materials so as to obtain traditional Chinese medicines; (2) crushing, namely crushing the obtained traditional Chinese medicines into granules not greater than 5mm by usinga crushing machine; (3) performing microwave sterilization, namely performing sterilization treatment on crushed traditional Chinese medicine granules in a microwave sterilization tank, and conveyingthe sterilized traditional Chinese medicines for later use in next procedures, wherein the sterilization temperature is 60-80 DEG C, and the sterilization time is 30-60 minutes. The process disclosedby the invention is low in sterilization temperature and rapid in speed, and thus loss of effective components of medicines is reduced.

Description

technical field [0001] The invention relates to a microwave sterilization process for Chinese medicinal materials. Background technique [0002] Chinese herbal medicines will be polluted by the outside world during storage and transportation, and they must be sterilized before use. The sterilization methods commonly used in the production process of traditional Chinese medicines are: ①moist heat steam sterilization; ②microwave sterilization; ③Co60 radiation Sterilize. (The other two sterilization methods: ozone sterilization and ethylene oxide sterilization are rarely used because they cannot be used for large-scale production of traditional Chinese medicine). These sterilization methods have their own disadvantages or imperfections to varying degrees, which will ultimately affect the stability of the product quality of Chinese patent medicines, the strict implementation of GMP standards for drug production, and energy saving and consumption reduction: ① Moist heat steam st...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61L2/12
CPCA61L2/0064A61L2202/21
Inventor 黄祖建
Owner CHONGQING HUAAO PHARMA IND CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products