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Cell culture module and cell culture system

A cell culture and cell technology, applied in the field of biomedical cell culture, can solve problems such as poor passability

Pending Publication Date: 2018-04-13
SHANGHAI BAIZE MEDICAL APP & INSTR CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The system is highly integrated, detachable or sealed, and has automatic real-time monitoring. For the culture of vascularized tissue, the passability is not strong

Method used

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  • Cell culture module and cell culture system
  • Cell culture module and cell culture system
  • Cell culture module and cell culture system

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Embodiment Construction

[0090] The present invention will be described below in combination with specific embodiments. It should be understood that these embodiments are only used to illustrate the present invention and are not intended to limit the scope of the present invention. Other aspects of the invention will be apparent to those skilled in the art from the disclosure herein.

[0091] The cell culture system of the present invention is a chip type immune cell culture system (device). The cell culture device of the present invention can realize a new immune cell culture scheme, and can independently process the cell culture of each clinical patient sample. By taking a certain amount of cells, especially immune cells, from the patient's body, and putting them into the culture system of the present invention for culture, a corresponding number of target cells can be finally obtained, such as DC cells. 8 In terms of the total number, the number of T cells expanded and the scale of cultured cells...

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PUM

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Abstract

The invention relates to a cell culture module and a cell culture system. The cell culture module comprises a sealed body, a culture solution cavity and a cell cavity, a sealing stopping block and hollow fiber yarns, wherein the sealed body is communicated with the outer side through a culture solution inlet, a culture solution outlet, a cell sap inlet and a cell sap outlet; the culture solution cavity and the cell cavity are located in the body; the culture solution cavity comprises a culture solution cavity communicated with the culture solution inlet and a culture solution cavity communicated with the culture solution outlet, which are independent; the cell cavity is communicated with the cell sap inlet and the cell sap outlet; the sealing stopping block is used for separating to form the cell cavity and the culture solution cavity; the hollow fiber yarns are arranged on walls of the cell cavity and are provided with micro-pores which do not allow cells to pass; the hollow fiber yarns penetrate through the sealing stopping block; two ends of the hollow fiber yarns are communicated with the culture solution cavity located at a culture solution inlet end and the culture solution cavity located at a culture solution outlet end respectively. The cell culture system comprises a cell culture chip and can be used for culturing various cells.

Description

technical field [0001] The invention belongs to the field of biomedical cell culture, and in particular relates to a cell culture module and a cell culture system. Background technique [0002] Nowadays, biological immunotherapy has become an emerging method to overcome tumors and cancers. It is a key technology in the field of biotherapy technology and has good research and development and application prospects. Cell therapy in biological immunotherapy is to extract and sort a certain amount of immune cells from patients, and expand and culture them in vitro. This process may include the addition of specific stimulating factors and / or the use of transgenic technology. When the cells expand to After a certain scale or quantity, it will be injected back into the patient's body according to the patient's course of treatment. During the entire treatment process, the in vitro expansion and culture of immune cells is an important part of technical realization, and a reasonable c...

Claims

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Application Information

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IPC IPC(8): C12M3/00C12M3/02C12M1/38C12M1/34
CPCC12M25/02C12M37/04C12M41/12C12M41/34C12M41/48
Inventor 钱其军周进师传胤颜开冬
Owner SHANGHAI BAIZE MEDICAL APP & INSTR CO LTD
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