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A kind of skin wound biologically induced active dressing and its preparation method and application

A technology for inducing activity and skin wounds, applied in medical science, absorbent pads, bandages, etc., it can solve the problems that the efficacy of promoting wound healing needs to be improved, the use requirements cannot be met, and the use process is inconvenient, so as to achieve the effect of promoting healing and absorption. The ability of exudate is strong, the effect of strong moisturizing performance

Active Publication Date: 2020-09-01
GUANGZHOU RAINHOME PHARM&TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent application 105854069A discloses an alginate dressing containing a drug for promoting wound healing and a preparation method thereof. The alginate dressing includes the following components: 50-99.9 parts of alginate, 0.1-25 parts of a drug for promoting wound healing and 0.01 to 15 parts of surfactant; the invention contains alginate dressings that promote wound healing, which can be used to heal difficult wounds and tissue defect wounds, absorb exudate, provide a moist environment for wound healing, and effectively promote wound healing , but its efficacy in promoting wound healing needs to be improved
However, liquid dressings are usually in a liquid state, have poor stability, are inconvenient to use, and cannot meet people's use requirements.

Method used

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  • A kind of skin wound biologically induced active dressing and its preparation method and application
  • A kind of skin wound biologically induced active dressing and its preparation method and application

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1, a kind of biological induction active dressing of skin wound

[0027] The skin wound bio-inducing active dressing consists of the following components and their parts by weight:

[0028] 18 parts of chitosan polymer, 50 parts of sodium alginate, 9 parts of sodium phenytoin, 12 parts of strontium-doped borate bioactive glass, 10 parts of spirulina powder, 22 parts of ethanol, 13 parts of glycerin and 200 parts of water for injection; The chitosan polymer is composed of carboxymethyl chitosan and chitosan hydrochloride in a weight ratio of 2:1; the chemical composition of the strontium-doped borate bioactive glass is Na 2 O-K 2 O-MgO-CaO-B 2 o 3 -SiO 2 -P 2 o 5 -SrO, the molar ratio of each component is 6:8:8:22:18:32:2:4.

[0029] Preparation:

[0030] S1. Take half of the water for injection, add chitosan polymer and stir well, add phenytoin sodium and spirulina powder, stir evenly, remove air bubbles, transfer to a sterilizing tank at 115°C for st...

Embodiment 2

[0033] Embodiment 2, a kind of biological induction active dressing of skin wound

[0034] The skin wound bio-inducing active dressing consists of the following components and their parts by weight:

[0035] 20 parts of chitosan polymer, 40 parts of sodium alginate, 7 parts of sodium phenytoin, 15 parts of strontium-doped borate bioactive glass, 8 parts of spirulina powder, 19 parts of ethanol, 15 parts of glycerin and 250 parts of water for injection. The chitosan polymer is composed of carboxymethyl chitosan and chitosan hydrochloride in a weight ratio of 3:2; the chemical composition of the strontium-doped borate bioactive glass is Na 2 O-K 2 O-MgO-CaO-B 2 o 3 -SiO 2 -P 2 o 5 -SrO, the molar ratio of each component is 6:8:8:22:18:32:2:4.

[0036] Preparation:

[0037] S1. Take half of the water for injection, add chitosan polymer and stir well, add phenytoin sodium and spirulina powder, stir evenly, remove air bubbles, transfer to a sterilizing tank at 125°C for ste...

Embodiment 3

[0040] Embodiment 3, a kind of biological induction active dressing of skin wound

[0041] The skin wound bio-inducing active dressing consists of the following components and their parts by weight:

[0042] 22 parts of chitosan polymer, 30 parts of sodium alginate, 5 parts of sodium phenytoin, 18 parts of strontium-doped borate bioactive glass, 5 parts of spirulina powder, 16 parts of ethanol, 17 parts of glycerin and 300 parts of water for injection; The chitosan polymer is composed of carboxymethyl chitosan and chitosan hydrochloride in a weight ratio of 4:3; the chemical composition of the strontium-doped borate bioactive glass is Na 2 O-K 2 O-MgO-CaO-B 2 o 3 -SiO 2 -P 2 o 5 -SrO, the molar ratio of each component is 6:8:8:22:18:32:2:4.

[0043] Preparation:

[0044] S1. Take half the amount of water for injection, add chitosan polymer and stir well, add phenytoin sodium and spirulina powder, stir evenly, remove air bubbles, transfer to a sterilizing tank at 135°C ...

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Abstract

The invention belongs to the technical field of medicine materials, and in particular relates to skin wound bio-induced active dressing, and a preparation method and application thereof. The skin wound bio-induced active dressing comprises the following components in parts by weight: 18 to 22 parts of chitosan polymer, 30 to 50 parts of sodium alginate, 5 to 9 parts of dilantin, 12 to 18 parts ofstrontium borate doped bioactive glass, 5 to 10 parts of spirulina powder, 16 to 22 parts of ethanol, 13 to 17 parts of glycerinum and 200 to 300 parts of water for injection. The skin wound bio-induced active dressing provided by the invention is scientific and reasonable in compatibility, the components are interacted, the optimal environment is provided for growth and healing of wound, and remarkable bacteriostatic, inflammation-diminishing and analgesic effects are achieved; in addition, the bioactive glass serving as a carrier not only can control the release speed of the effective components in the dressing, but also can effectively promote healing of the wound and shorten the healing time.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to a biologically induced active dressing for skin wounds and a preparation method and application thereof. Background technique [0002] Medical dressings refer to medical materials that cover wounds, temporarily protect wounds, prevent infection, and promote healing. Human skin is a barrier to maintain the stability of the internal environment and prevent the invasion of microorganisms. Skin trauma caused by ulcers, burns, etc. will cause a series of problems, such as infection, water loss, and immune system dysfunction. Dressings generally absorb exudate, Keeping the wound surface moist and providing a favorable environment for wound repair by preventing bacterial contamination of the wound and new tissue growth. [0003] Traditional dressings commonly used in clinical practice, such as various gauze, cotton pads, etc., are mostly processed from cotton, sof...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/28A61L15/20A61L15/18A61L15/40A61L15/44A61L15/46
Inventor 车七石
Owner GUANGZHOU RAINHOME PHARM&TECH CO LTD
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