transdermal liquid formulation
A liquid preparation, absorption type technology, applied in the field of external preparation composition, can solve the problem of shortening transdermal absorption, and achieve the effect of reducing skin irritation and shortening lag time
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[0042] [Lizatriptan-containing liquid preparations]
[0043] Liquid formulations with the ingredients (wt %) shown in Table 1 were prepared. The obtained liquid preparation was subjected to an in vivo blood drug concentration evaluation test using rats. The results of the blood drug concentration (ng / ml) of rizatriptan at each blood sampling point are listed in Table 1 together. also, figure 1 It is a schematic diagram of the transition of blood drug concentration.
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