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Medical traditional Chinese medicine coupling agent and preparation method thereof

A coupling agent and traditional Chinese medicine technology, which is applied in the field of clinical medical testing, can solve the problems affecting the accuracy of ultrasonic diagnosis and corroding the ultrasonic probe, and achieve good sterilization effect, wide antibacterial effect and fast sterilization effect

Inactive Publication Date: 2017-11-07
苏州凌科特新材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the extracts of traditional Chinese medicine are insoluble in water, so it is often necessary to add non-aqueous solvents and emulsifiers, which will corrode the ultrasound probe and affect the accuracy of ultrasound diagnosis to a certain extent

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A traditional Chinese medicine type medical coupling agent prepared from the following raw materials in parts by weight: 4 parts of guar gum, 2.2 parts of carbomer, 1.4 parts of menthol, 0.6 parts of lysine, 1.5 parts of potassium triethyldiaminetetraacetate Parts, 1.2 parts of anisaldehyde, 0.8 parts of theaspirane, 1.3 parts of baicalin, 1.8 parts of compound Chinese medicine extract, 0.6 parts of triisopropanolamine, 0.3 parts of phosphoric acid, 16 parts of glycerol, and 38 parts of distilled water.

[0024] Wherein, the raw materials of the compound Chinese medicinal extract are Sichuan-Yunnan Elsholtzia, rue leaves, buckwheat flower, coral ginger, dill, basil, mass ratio 1:1.3:1.8:0.4:1.2:2.7:1.3:0.9:1.6 Toad clothes, dog's tail grass and barbata.

[0025] Wherein, the extraction step of the compound Chinese medicine extract is: weigh the raw materials of Chinese medicine in parts by weight, crush them into coarse powder particles, pass through a 20-mesh sieve, then so...

Embodiment 2

[0032] A traditional Chinese medicine type medical coupling agent prepared from the following parts by weight of raw materials: 9 parts of guar gum, 7.5 parts of carbomer, 5 parts of menthol, 2.5 parts of lysine, and 3.2 parts of potassium triethyldiaminetetraacetate Parts, 2.4 parts of anisaldehyde, 2.1 parts of theaspirane, 2.7 parts of baicalin, 2.9 parts of compound Chinese medicine extract, 2 parts of triisopropanolamine, 1.2 parts of phosphoric acid, 22 parts of glycerol, 50 parts of distilled water.

[0033] Wherein, the raw materials of the compound Chinese medicinal extract are Sichuan-Yunnan Elsholtzia, rue leaves, buckwheat flower, coral ginger, dill, basil, mass ratio 1:1.3:1.8:0.4:1.2:2.7:1.3:0.9:1.6 Toad clothes, dog's tail grass and barbata.

[0034] Wherein, the extraction step of the compound Chinese medicine extract is: weigh the raw materials of Chinese medicine in parts by weight, crush them into coarse powder particles, pass through a 20-mesh sieve, then soak a...

Embodiment 3

[0041] A traditional Chinese medicine type medical coupling agent prepared from the following raw materials in parts by weight: 4.5 parts of guar gum, 2.4 parts of carbomer, 1.8 parts of menthol, 0.8 parts of lysine, and 1.7 parts of potassium triethyldiaminetetraacetate Parts, anisaldehyde 1.5 parts, theaspirane 1.1 parts, baicalin 1.5 parts, compound Chinese medicine extract 2.1 parts, triisopropanolamine 0.8 parts, phosphoric acid 0.5 parts, glycerol 18 parts, and 40 parts distilled water.

[0042] Wherein, the raw materials of the compound Chinese medicinal extract are Sichuan-Yunnan Elsholtzia, rue leaves, buckwheat flower, coral ginger, dill, basil, mass ratio 1:1.3:1.8:0.4:1.2:2.7:1.3:0.9:1.6 Toad clothes, dog's tail grass and barbata.

[0043] Wherein, the extraction step of the compound Chinese medicine extract is: weigh the raw materials of Chinese medicine in parts by weight, crush them into coarse powder particles, pass through a 20-mesh sieve, then soak and decoct with...

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Abstract

The invention discloses a medical traditional Chinese medicine coupling agent and a preparation method thereof. The medical traditional Chinese medicine coupling agent is prepared from the following raw materials: guar gum, Carbomer, menthol, lysine, potassium triethylenediamine tetraacetate, anisic aldehyde, theaspirane, baicalin, compound traditional Chinese medicine extract, triisopropanolamine, phosphoric acid, glycerinum and distilled water. The medical coupling agent provided by the invention has good sterilizing effect both for bacteria and pathogenic fungi, and is wide in antibiosis and fast in sterilization. In addition, an ultrasonic attenuation value of the medical coupling agent is small, no irritation phenomenon is present, a probe is not corroded and damaged, various performance indexes are hardly changed when the medical traditional Chinese medicine coupling agent is stored for a year at room temperature, the stability is excellent, and the sensitization and various performance indexes of a delayed hypersensitivity test specimen are good.

Description

Technical field [0001] The invention belongs to the technical field of clinical medicine detection, and specifically relates to a traditional Chinese medicine type medical coupling agent and a preparation method thereof. Background technique [0002] When ultrasonic waves are incident on the interface of two different media, the greater the antagonism between the two, the less the sound energy that enters the other media through the interface. If the ultrasound probe is in direct contact with the skin and there is air, the emitted ultrasound cannot reach and enter the human body. Therefore, medical ultrasound couplants are usually used and applied between the probe and the skin surface to isolate the air. , So that the ultrasound can spread smoothly. There are several basic requirements for medical ultrasound coupling agents: 1) Good biocompatibility, in line with the relevant regulations of medical supplies, that is, no cytotoxicity in contact within 24 hours, and no skin irrit...

Claims

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Application Information

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IPC IPC(8): A61K49/22A61K36/9068A61P31/04A61P31/10A61P31/02A61K31/7048A61K31/045A61K31/198A61K31/11
CPCA61K31/045A61K31/11A61K31/198A61K31/7048A61K36/185A61K36/23A61K36/53A61K36/539A61K36/68A61K36/70A61K36/75A61K36/9068A61K49/22A61K2236/331A61K2236/51A61K2300/00
Inventor 金可心
Owner 苏州凌科特新材料有限公司
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