Microfluidic pipettor spearhead

A pipette and microfluidic technology, applied in the direction of laboratory equipment, measuring tubes/pipettes, chemical instruments and methods, etc., can solve the problems of lack of high-throughput microfluidic concentration methods, etc., and achieve simple structure, The effect of high work efficiency and high throughput

Active Publication Date: 2017-09-15
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, there is still a lack of devices and high-throughput microfluidic concentration methods that can be directly used with simple tools commonly used in laboratories.

Method used

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  • Microfluidic pipettor spearhead
  • Microfluidic pipettor spearhead
  • Microfluidic pipettor spearhead

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Experimental program
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Embodiment Construction

[0025] The present invention will be described in further detail below in conjunction with the accompanying drawings.

[0026] like Figure 1-4 As shown, the microfluidic pipette tip of the present invention includes a body 1 and an outer capsule 2 . Components can be obtained by injection molding, machining or 3D printing. The main body 1 is preferentially formed by 3D printing as a whole to obtain parts with high precision, or it can also be assembled through precision machining of multiple components. The main body 1 and the outer bag 2 are screwed and connected through the corresponding non-sealed threads 11 provided at the respective tails, and a cavity 5 is formed between them. The cavity 5 communicates with the blank liquid outlet 4 arranged on the outer surface of the body 1, and is used to store the blank liquid. The cavity 5 is kept in communication with the outside through a non-sealed thread 11 at one end of the tail to prevent the internal pressure of the cavity ...

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Abstract

The invention discloses a microfluidic pipettor spearhead. The microfluidic pipettor spearhead comprises a body and an external capsule, the body comprises a liquid inlet channel arranged in a body tail area, several condensation micro channels arranged along the circumferential part of the body, a blank liquid outlet arranged on the external surface of the body, and a liquid outlet channel arranged in a body head area; the condensation micro channel comprises a direct flow channel, a bifurcation channel, an intermediate flow channel and two side branch channels, one end of the direct flow channel is communicated with the liquid inlet channel, the other end and the bifurcation channel are communicated, one end of the intermediate flow channel and the bifurcation channel are communicated, the other end is communicated with the liquid outlet channel, two side branch channels are respectively arranged at two sides of the intermediate flow channel, one end of the side branch channel is communicated with the bifurcation channel, and the other end is bent to the external surface of the body and is communicated with the blank liquid outlet. The microfluidic pipettor spearhead has a simple structure and high flux, and concentration of micro-size particles can be realized by using microfluid inertia effect.

Description

technical field [0001] The invention relates to a pipette tip, in particular to a microfluidic pipette tip for rapid concentration of micron particles and cells. Background technique [0002] Concentration of tangible solid components such as micron particles and cells is a technical means widely used in biochemical, pharmaceutical, food and environmental industries. Traditional particle or cell concentration is achieved by microporous membrane filtration or high-speed centrifugation. Microporous membrane filtration selects a filter membrane with pores smaller than the particle or cell size, so that the particle or cell is blocked on the membrane, and the blank liquid is filtered out to increase the concentration of the sample. However, how to elute and collect particles or cells from microporous membranes is still a formidable challenge. In addition, the microporous membrane filtration method has problems such as membrane pore clogging, low concentration efficiency, and p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/02
CPCB01L3/0275B01L2200/027B01L2300/0861
Inventor 项楠蒋丰韬倪中华
Owner SOUTHEAST UNIV
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