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Pharmaceuticalcomposition for treating lung cancer and application thereof

A composition and lung cancer technology, applied in the field of medicine, can solve the problems of drug compositions for the treatment of lung cancer with no effect, and achieve the effects of improving cellular immune function, improving quality of life, and high safety

Inactive Publication Date: 2017-09-08
淮安市中医院 +2
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] But have not found the medicinal composition that effect is notable at present and is applied to the treatment of lung cancer

Method used

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  • Pharmaceuticalcomposition for treating lung cancer and application thereof
  • Pharmaceuticalcomposition for treating lung cancer and application thereof
  • Pharmaceuticalcomposition for treating lung cancer and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0036] The present invention will be described in detail below in conjunction with specific clinical trials.

[0037] Pemetrexed was purchased from Yangzijiang Pharmaceutical Group; docetaxel and cisplatin were purchased from Jiangsu Hengrui Medicine Co., Ltd.

[0038] Preparation of the herbal composition: American ginseng and agrimony were mixed according to the weight ratio of 1:1, thickly decocted in 250ml, and then sterilized to make a preparation, 250ml / bottle for later use.

[0039] 1 Materials and methods

[0040] 1.1 Diagnostic criteria The diagnostic criteria of the disease refer to the National Health and Family Planning Commission's "Chinese Standards for the Diagnosis and Treatment of Primary Lung Cancer (2015 Edition)".

[0041] The diagnostic criteria of TCM symptoms refer to the lung cancer chapter of "Internal Medicine of Traditional Chinese Medicine" 7th edition. Thinness and aversion to wind, spontaneous sweating or night sweating, dry mouth and less drink...

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Abstract

The invention discloses a pharmaceuticalcomposition for treating lung cancer. The pharmaceuticalcomposition comprises(1) aherbal medicinecomposition from radix panacisquinquefolii and herba agrimoniae or an extract of the herbal medicinecomposition, and (2) one or more compounds for cancer chemotherapy. The pharmaceuticalcomposition belongs to herbal medicinecompositions combined with chemotherapy drugs, is applied to patients with advanced lung cancer, particularly patients with qi-yin deficiency advanced lung cancer, and can obviously improve the cellular immune function, particularly in terms of lymphocyte subpopulation.Compared with a control group, the difference of CD4+, CD4+ / CD8+ and CD16+56+ of a test group after treatment have statistical significance; compared with the control group, difference in gradation of emotion, total life quality, fatigue, anhelation and lung cancerrelated symptoms have difference in gradation in terms of life quality. Through the application of the pharmaceuticalcomposition, the patient compliance is good, adverse effects do not exist, the safety is high, and the pharmaceuticalcomposition is suitable for clinical expansion.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a pharmaceutical composition for treating lung cancer and its application. Background technique [0002] Lung cancer is the disease with the highest incidence of cancer in the world. It is the leading cause of cancer death in men and the second leading cause of cancer death in women. Low-income and middle-income countries account for more than 50% of lung cancer deaths every year [1] . In 2012, there were 1.8 million new lung cancer patients and 1.59 million deaths in the world, and China accounted for more than 1 / 3 of the total cases, ranking first in the incidence and mortality of cancer in China [2] . The treatment of lung cancer is mainly based on surgery, radiotherapy and chemotherapy, molecular targeted therapy and traditional Chinese medicine, but more than half of the patients are in the advanced stage when they are first diagnosed [3] , there is no opportunity for ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61P35/00A61K31/519A61K31/337A61K33/24
CPCA61K31/337A61K31/519A61K33/24A61K36/258A61K36/73A61K2300/00
Inventor 马骏高广毅陈爱飞霍介格
Owner 淮安市中医院
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