Traditional Chinese medicine composition with effects of clearing away heat and toxic materials as well as preparation method and drug preparation thereof

A heat-clearing and detoxifying technology and pharmaceutical preparation technology, applied in the field of pharmaceutical preparations, traditional Chinese medicine compositions with heat-clearing and detoxifying effects and their preparations, can solve the problems of product technology and curative effect that need to be further improved, and achieve significant pharmacological effects, good therapeutic effects, and products The effect of quality and curative effect guarantee

Inactive Publication Date: 2017-09-05
HEILONGJIANG ZBD PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the commonly used extraction process is to decoct the four herbs such as honeysuckle and other herbs together for preparation, but the product process and curative effect need to be further improved

Method used

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  • Traditional Chinese medicine composition with effects of clearing away heat and toxic materials as well as preparation method and drug preparation thereof
  • Traditional Chinese medicine composition with effects of clearing away heat and toxic materials as well as preparation method and drug preparation thereof
  • Traditional Chinese medicine composition with effects of clearing away heat and toxic materials as well as preparation method and drug preparation thereof

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preparation example Construction

[0032] The second aspect of the present invention provides a preparation method of a traditional Chinese medicine composition with heat-clearing and detoxifying effects, comprising the following steps:

[0033] 1. Preparation of total volatile oil

[0034]400-600 parts by weight of honeysuckle, 800-1200 parts of forsythia and 400-600 parts of isatidis are distilled and extracted in 3-12 times the amount of water, and the extracted distillate is distilled again to obtain rectified liquid. The rectification liquid is the total volatile oil including honeysuckle volatile oil, forsythia volatile oil and Radix Radix volatile oil. The aqueous solution and dregs obtained after distillation are collected for future use.

[0035] One of the active ingredients in honeysuckle, forsythia and isatis root: the volatile oil is extracted separately by distillation, so as to avoid the loss of volatile oil during the cooking process, thereby increasing the content of active ingredients in the ...

Embodiment 1

[0058] The traditional Chinese medicine composition with heat-clearing and detoxifying effects of this embodiment contains baicalin, chlorogenic acid, luteolin, forsythiaside a, (R, S)-Gaoyichun, total volatile oil and forsythin in a weight ratio of 560: 12: 1: 11: 6: 52: 6. The above-mentioned Chinese medicine composition is prepared according to the following preparation method:

[0059] 400 parts by weight of honeysuckle, 800 parts of forsythia and 600 parts of isatidis were distilled and extracted once in 3 times the amount of water, and the extraction time was 5 hours. The extracted distillate is distilled again to obtain the rectified liquid, which is the total volatile oil including honeysuckle volatile oil, forsythia volatile oil and isatidis root volatile oil. The aqueous solution obtained after the distillation is collected and filtered for later use, and the medicinal residue is for later use. The total volatile oil and cyclodextrin were clathrated at a weight rat...

Embodiment 2

[0065] The traditional Chinese medicine composition with heat-clearing and detoxifying effects of this embodiment contains baicalin, chlorogenic acid, luteolin, forsythiaside a, (R, S)-Gaoyichun, total volatile oil and forsythin in a weight ratio of 180:36:3.3:21:3.9:97:17.

[0066] The above-mentioned Chinese medicine composition is prepared according to the following preparation method:

[0067] 500 parts by weight of honeysuckle, 1000 parts of forsythia and 500 parts of isatidis were distilled and extracted in 8 times the amount of water for 3 times, and the extraction time was 3 hours each time. The extracted distillates are combined and distilled again to obtain a rectification liquid, which is the total volatile oil including honeysuckle volatile oil, forsythia volatile oil and Radix Radix isatidis volatile oil. The aqueous solution obtained after the distillation is collected and filtered for later use, and the medicinal residue is for later use. The total volatile oi...

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Abstract

The invention relates to a traditional Chinese medicine composition with effects of clearing away heat and toxic materials as well as preparation method and drug preparation thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition with effects of clearing away heat and toxic materials comprises baicalin, chlorogenic acid, galuteolin, forsythiaside a, (R, S)-epigoitrin and total volatile oil, wherein a weight ratio of the baicalin to chlorogenic acid to galuteolin to forsythiaside a to (R, S)-epigoitrin to total volatile oil is (150-600):(10-60):(1-6):(10-50):(2-9):(50-200); and the total volatile oil is extracted from lonicera japonica, fructus forsythia and isatis root. The traditional Chinese medicine composition disclosed by the invention is high in content of active ingredients and excellent in curative effect of the product.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition with heat-clearing and detoxifying effects, a preparation method thereof and a pharmaceutical preparation. Background technique [0002] Traditional medicine believes that "at the beginning of a febrile disease, there will be fever, slight aversion to wind and cold, no sweat or sweating is not smooth; wind-heat attack will cause sore throat and cough; , heat-clearing and detoxifying." Honeysuckle, Forsythia, and Radix Radix are all good medicines for clearing away heat and detoxifying. Scutellaria baicalensis is a plant of Labiatae. Its root is used as medicine. It tastes bitter and cold in nature. [0003] Although honeysuckle, scutellaria baicalensis, forsythia and isatidis are traditional Chinese medicines in my country, in order to make the medicinal composition after compatibility exert better curative effect, for a long...

Claims

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Application Information

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IPC IPC(8): A61K36/634A61K47/69A61P29/00A61P39/02A61K31/216A61K31/421A61K31/7032A61K31/7048
CPCA61K31/216A61K31/421A61K31/7032A61K31/7048A61K36/195A61K36/315A61K36/355A61K36/634A61K2236/331A61K2300/00
Inventor 方同华许照芹崔玉海陈晨
Owner HEILONGJIANG ZBD PHARMA
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