An anti-oxidant composite traditional Chinese medicine extract and preparation method thereof

An isolate and anti-oxidation technology, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, anti-toxins, etc., can solve the problems of weak anti-oxidation and inability to effectively scavenge free radicals

Inactive Publication Date: 2017-06-09
宋淑芹
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Technical problem to be solved: There are many ingredients in conventional Chinese medicines that have antioxidant effects, but their antioxidant effects are weak and cannot effectively remove free radicals. It is necessary to extract and separate the ingredients of traditional Chinese medicines that have antioxidant effects. Carry out rational combination, to improve its antioxidant activity, therefore need a kind of antioxidation compound traditional Chinese medicine extract isolate and preparation method thereof

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] (1) pulverize after purslane is dried, pulverize and extract with water, extraction temperature is room temperature, extraction time is 4h, and the weight of water is 4 times of purslane weight, gets supernatant after leaching, will Purslane water extract was obtained after the supernatant was concentrated in vacuum; (2) mallow seeds were pulverized with a pulverizer, and ethanol was added after pulverization for extraction. The extraction temperature was 50°C, the extraction time was 40min, and the solid-liquid ratio was 1 : 7, after the extraction, the extract is filtered with a filter cloth, after the filtration, the filtrate is vacuum-concentrated until no ethanol flows out, and the concentrate is collected, and the concentrate is the ethanol extract of mallow seed; (3) the dried fishy smell Grass is crushed, then extracted with ethanol, the extraction temperature is 65°C, the extraction time is 30min, the ratio of solid to liquid is 1:3, after extraction, it is cent...

Embodiment 2

[0022](1) pulverize after purslane is dried, pulverize and extract with water, extraction temperature is room temperature, extraction time is 4h, and the weight of water is 4 times of purslane weight, gets supernatant after leaching, will Purslane water extract was obtained after the supernatant was concentrated in vacuum; (2) mallow seeds were pulverized with a pulverizer, and ethanol was added after pulverization for extraction. The extraction temperature was 50°C, the extraction time was 40min, and the solid-liquid ratio was 1 : 7, after the extraction, the extract is filtered with a filter cloth, after the filtration, the filtrate is vacuum-concentrated until no ethanol flows out, and the concentrate is collected, and the concentrate is the ethanol extract of mallow seed; (3) the dried fishy smell Grass is crushed, then extracted with ethanol, the extraction temperature is 65°C, the extraction time is 30min, the ratio of solid to liquid is 1:3, after extraction, it is centr...

Embodiment 3

[0024] (1) pulverize after purslane is dried, pulverize and extract with water, extraction temperature is room temperature, extraction time is 4h, and the weight of water is 4 times of purslane weight, gets supernatant after leaching, will Purslane water extract was obtained after the supernatant was concentrated in vacuum; (2) mallow seeds were pulverized with a pulverizer, and ethanol was added after pulverization for extraction. The extraction temperature was 50°C, the extraction time was 40min, and the solid-liquid ratio was 1 : 7, after the extraction, the extract is filtered with a filter cloth, after the filtration, the filtrate is vacuum-concentrated until no ethanol flows out, and the concentrate is collected, and the concentrate is the ethanol extract of mallow seed; (3) the dried fishy smell Grass is crushed, then extracted with ethanol, the extraction temperature is 65°C, the extraction time is 30min, the ratio of solid to liquid is 1:3, after extraction, it is cent...

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Abstract

The invention belongs to the field of traditional Chinese medicine, and discloses an anti-oxidation compound Chinese medicine extract isolate and a preparation method thereof. The anti-oxidation compound Chinese medicine extract comprises the following extract isolate by weight: purslane water extract 48 parts, 614 parts of ethanol extract of mallow seed, 25 parts of ethanol extract of Houttuynia cordata, and 510 parts of supercritical extract of Baiziren. The preparation method of the anti-oxidation compound traditional Chinese medicine extract and isolate includes water extraction, alcohol extraction, supercritical extraction, column separation and other steps. The prepared composite traditional Chinese medicine extract has a remarkable effect of scavenging superoxide anion free radicals, and improves the antioxidant performance of the traditional Chinese medicine.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and relates to a composite traditional Chinese medicine extraction isolate and a preparation method thereof, in particular to an antioxidant composite traditional Chinese medicine extraction isolation and a preparation method thereof. Background technique [0002] Free radicals are intermediate metabolites of various biochemical reactions in human life activities. They have high chemical activity and are the effective defense system of the body. If they cannot be maintained at a certain level, they will affect the life activities of the body. However, if there are too many free radicals and cannot be removed in time, they will attack the life macromolecules and various organelles in the body, causing various damages to the body at the molecular level, cell level, and tissue and organ level, and accelerate the aging process of the body and induce various diseases. [0003] Superoxide ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/78A61P39/06
Inventor 宋淑芹
Owner 宋淑芹
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