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Western medicine composition for treating coronary heart diseases and preparation method thereof

A technology for coronary heart disease and western medicine, applied in the field of pharmaceutical preparation, can solve problems such as obvious side effects, long cycle, recurrence, etc., achieve significant curative effect, and eliminate myocardial ischemia and myocardial infarction coronary heart disease.

Inactive Publication Date: 2017-05-31
HENAN TIMECLOUD COMM TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The treatment of coronary heart disease includes drug therapy, interventional therapy, surgical treatment, rehabilitation of coronary heart disease, etc., but in general, the current treatment effect for coronary heart disease is not satisfactory, especially the treatment of traditional Chinese medicine, which takes a long time and often recurs , and the side effects are obvious

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A western medicine combination for treating coronary heart disease, the main raw materials in parts by weight are: 8 parts of simvastatin, 17 parts of aliskiren, 5 parts of propranolol, 2 parts of isosorbide 5-mononitrate, 11 parts of aspirin, 1.5 parts of heparin, 0.5 parts of crospovidone, 8 parts of seaweed polysaccharide, 2 parts of 3-ethyl-(4-aminophenyl)-piperidinedione.

[0017] A preparation method of a western medicine combination for treating coronary heart disease, the specific steps are:

[0018] First, in a pharmaceutical-grade clean area, weigh simvastatin, cannabinoid A, propranolol, 5-isosorbide mononitrate, aspirin, heparin, crospovidone, seaweed polysaccharide, 3- Ethyl-(4-aminophenyl)-piperidinedione, sieved, mechanically mixed, added ultrapure water, placed in a pharmaceutical mixer, mixed for 4min, controlled RSD≤5%, after mixing, pressed into tablets and dried at low temperature , the temperature is controlled at 4°C, and the western medicine comb...

Embodiment 2

[0020] A western medicine combination for treating coronary heart disease, the main raw materials in parts by weight are: 11 parts of simvastatin, 19 parts of aliskiren, 8 parts of propranolol, 2 parts of isosorbide 5-mononitrate, 14 parts of aspirin, 1.5 parts of heparin, 0.8 parts of crospovidone, 10 parts of seaweed polysaccharide, 2 parts of 3-ethyl-(4-aminophenyl)-piperidinedione.

[0021] A preparation method of a western medicine combination for treating coronary heart disease, the specific steps are:

[0022] First, in a pharmaceutical-grade clean area, weigh simvastatin, cannabinoid A, propranolol, 5-isosorbide mononitrate, aspirin, heparin, crospovidone, seaweed polysaccharide, 3- Ethyl-(4-aminophenyl)-piperidinedione, sieved, mechanically mixed, added ultrapure water, placed in a pharmaceutical mixer, mixed for 4min, controlled RSD≤5%, after mixing, pressed into tablets and dried at low temperature , the temperature is controlled at 4°C, and the western medicine co...

Embodiment 3

[0024] A western medicine combination for treating coronary heart disease, the main raw materials in parts by weight are: 15 parts of simvastatin, 21 parts of aliskiren, 9 parts of propranolol, 4 parts of isosorbide 5-mononitrate, 16 parts of aspirin, 1.7 parts of heparin, 1.2 parts of crospovidone, 11 parts of seaweed polysaccharide, 3 parts of 3-ethyl-(4-aminophenyl)-piperidinedione.

[0025] A preparation method of a western medicine combination for treating coronary heart disease, the specific steps are:

[0026] First, in a pharmaceutical-grade clean area, weigh simvastatin, cannabinoid A, propranolol, 5-isosorbide mononitrate, aspirin, heparin, crospovidone, seaweed polysaccharide, 3- Ethyl-(4-aminophenyl)-piperidinedione, sieved, mechanically mixed, added ultrapure water, placed in a pharmaceutical mixer, mixed for 6min, controlled RSD≤5%, after mixing, pressed into tablets and dried at low temperature , the temperature is controlled at 6°C, and the western medicine co...

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PUM

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Abstract

The invention discloses a western medicine composition for treating coronary heart diseases. The western medicine composition comprises the following main raw materials in parts by weight: 8-19 parts of simvastatin, 17-25 parts of aliskiren, 5-10 parts of propranolol, 2-6 parts of 5-isosorbide mononitrate, 11-18 parts of aspirin, 1.5-1.8 part of heparin, 0.5-1.9 part of crospovidone, 8-15 parts of algal polysaccharide and 2-4 parts of 3-ethyl-(4-aminophenyl)-dioxopiperidine. The prepared western medicine composition can quickly eliminate myocardial ischemia and myocardial infarction coronary heart diseases, is remarkable in curative effect and ensures no recurrence for a long time after curing.

Description

technical field [0001] The invention relates to the field of medicine preparation, in particular to a western medicine combination for treating coronary heart disease. Background technique [0002] Coronary heart disease is the main killer of human health. With the acceleration of globalization, cardiovascular and cerebrovascular diseases have begun to spread in developing countries and become the number one cause of death in the world. The World Health Organization classifies coronary heart disease as follows: (1) Asymptomatic myocardial ischemia: also known as painless myocardial ischemia or occult myocardial ischemia, it refers to the objective evidence of myocardial ischemia (cardiac electrical activity, left Abnormalities of ventricular function, myocardial perfusion and myocardial metabolism), but lack of chest pain or subjective symptoms related to myocardial ischemia. (2) Angina pectoris type: refers to a group of clinical syndromes mainly manifested by paroxysmal c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/366A61K31/165A61K31/138A61K31/34A61K31/616A61K31/727A61K31/79A61K31/715A61K31/451A61P9/10
CPCA61K31/366A61K31/138A61K31/165A61K31/34A61K31/451A61K31/616A61K31/715A61K31/727A61K31/79
Inventor 不公告发明人
Owner HENAN TIMECLOUD COMM TECH CO LTD
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