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Traditional Chinese medicinal compound product and preparation method thereof

A technology for products and traditional Chinese medicines, applied in the field of traditional Chinese medicine compound products and their preparation, can solve the problems of low purity of extracts, consumption of toxic solvents, etc., and achieve the effects of abundant active ingredients, low cost and advanced preparation technology

Inactive Publication Date: 2017-05-10
FUJIAN TIANSIDUN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Alisma mainly uses solvent extraction, which consumes a lot of toxic solvents, and the purity of the extract is not high

Method used

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  • Traditional Chinese medicinal compound product and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A traditional Chinese medicine compound product, the main raw materials are: 3000 parts of Alisma, 2000 parts of Cordyceps militaris, 2000 parts of Poria cocos, 2000 parts of kudzu root and 1000 parts of lotus leaf in parts by weight. Alisma, Cordyceps militaris, Poria cocos, Pueraria lobata and lotus leaves are pulverized, hydrolyzed, enzymatically hydrolyzed, extracted, filtered, concentrated, spray-dried, granulated and packed into capsules.

[0023] The preparation method comprises the following steps:

[0024] (1) Weigh the net-selected Alisma, Cordyceps militaris, Poria cocos, Pueraria lobata and lotus leaves, crush them, and sieve them to a fineness of 20 mesh;

[0025] (2) Soak the pulverized powder in drinking water for 2 hours, the ratio of solid to liquid is 1kg:15kg, then add 1.0% cellulase and 1.0% amylase by weight of raw materials, and enzymolyze at 45°C for 150min; the cellulase The activity is 20000U / g, the amylase activity is 30000U / g, the enzyme is a...

Embodiment 2

[0033] A traditional Chinese medicine compound product, the main raw materials are: 3000 parts of Alisma, 2000 parts of Cordyceps militaris, 2000 parts of Poria cocos, 2000 parts of kudzu root and 1000 parts of lotus leaf in parts by weight. Alisma, Cordyceps militaris, Poria cocos, Pueraria lobata and lotus leaves are pulverized, hydrolyzed, enzymatically hydrolyzed, extracted, filtered, concentrated, spray-dried, granulated and packed into capsules.

[0034] The preparation method comprises the following steps:

[0035] (1) Weigh the net-selected Alisma, Cordyceps militaris, Poria cocos, Pueraria lobata and lotus leaves, crush them, and sieve them to a fineness of 60 mesh;

[0036] (2) Soak the pulverized powder in drinking water for 3 hours, the ratio of solid to liquid is 1kg:25kg, then add 1.5% cellulase and 1.5% amylase by weight of raw materials, and enzymolyze at 55°C for 180min; the cellulase The activity is 20000U / g, the activity of amylase is 30000U / g, and the pH o...

Embodiment 3

[0044] A traditional Chinese medicine compound product, the main raw materials are: 3000 parts of Alisma, 2000 parts of Cordyceps militaris, 2000 parts of Poria cocos, 2000 parts of kudzu root and 1000 parts of lotus leaf in parts by weight. Alisma, Cordyceps militaris, Poria cocos, Pueraria lobata and lotus leaves are pulverized, hydrolyzed, enzymatically hydrolyzed, extracted, filtered, concentrated, spray-dried, granulated and packed into capsules.

[0045] The preparation method comprises the following steps:

[0046] (1) Weigh the net-selected Alisma, Cordyceps militaris, Poria cocos, Pueraria lobata and lotus leaves, crush them, and sieve them to a fineness of 40 mesh;

[0047] (2) Soak the pulverized powder in drinking water for 2.5 hours, the ratio of solid to liquid is 1kg:20kg, then add 1.2% cellulase and 1.2% amylase by weight of raw materials, and enzymolyze at 50°C for 165min; the cellulase The activity is 20000U / g, the activity of amylase is 30000U / g, the enzyme...

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Abstract

The invention discloses a traditional Chinese medicinal compound product and a preparation method thereof. The preparation method comprises the following steps: crushing rhizoma alismatis, cordyceps militaris, poria, radix puerariae and folium nelumbinis, hydrolyzing the crushed materials, conducting enzymatic hydrolysis, conducting extraction, conducting filtering, conducting concentrating, conducting spray-drying, preparing granules and packaging the granules so as to obtain capsules. The product provided by the invention, which is prepared by extracting such medicinal materials as the rhizoma alismatis, the cordyceps militaris, the poria, the radix puerariae and the folium nelumbinis, is rich in active substances, safe and free from toxic and side effects; in comparison with a conventional Chinese herbal medicine processing extraction method, the method, which integrates modern biological extraction technology, has the advantages of being high in extraction yield, high in extraction speed, free from toxins, nonflammable, advanced in preparation process, free from environmental pollution and the like; the prepared rhizoma alismatis compound capsules are rich in active ingredients; and an efficient, environment-friendly and low-cost biotechnology for extracting the active substances from Chinese herbal medicines is provided.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound product and a preparation method thereof, in particular to a method for preparing a compound capsule containing Alisma, Cordyceps militaris, Poria cocos, Pueraria lobata, lotus leaf and other Chinese herbal medicine plants by using bioengineering technology. Background technique [0002] Since the beginning of the 21st century, human beings have paid more attention to health, and the research and development of natural medicinal plant products with Chinese characteristics has far-reaching significance to human health. At present, Alisma is mostly extracted by solvent, which consumes a lot of toxic solvents, and the purity of the extract is not high. Therefore, according to the medicinal properties and active ingredients of Alisma, Cordyceps militaris, Poria cocos, Pueraria lobata, lotus leaf and other Chinese herbal medicine raw materials, enzymatic hydrolysis, supercritical CO 2 Extract...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61K9/48
CPCA61K36/884A61K9/16A61K36/068A61K36/076A61K36/488A61K36/62A61K2236/19A61K2236/37A61K2236/51
Inventor 郭耀荣郭震宇吴松刚周云华
Owner FUJIAN TIANSIDUN BIOTECH
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