Application of beta-asarone to preparation of drugs for treating or preventing liver metastases of colorectal cancer

A technology of colorectal cancer and asarone, which is applied in the directions of drug combination, antitumor drugs, ether/aldol active ingredients, etc., to achieve the effect of easy popularization and application, improving survival rate and reducing liver metastasis

Active Publication Date: 2017-04-26
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, although chemotherapy has side effects, it is still the main battlefield for the treatment of tumors, especially tumors in the recurrent and metastatic stages.

Method used

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  • Application of beta-asarone to preparation of drugs for treating or preventing liver metastases of colorectal cancer
  • Application of beta-asarone to preparation of drugs for treating or preventing liver metastases of colorectal cancer
  • Application of beta-asarone to preparation of drugs for treating or preventing liver metastases of colorectal cancer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Get β-asarone 10g and Tween 5g, add polyethylene glycol and other drop pill bases, prepare 10g / kg β-asarone drop pills.

Embodiment 2

[0023] Take 10g of β-asarone, 5g of Tween, and 90g of sodium chloride, dilute to 1000ml with water, prepare an aqueous solution of β-asarone with a concentration of 10g / L, heat to dissolve, mix well, put it into a medicine bottle and seal it , sterilized, and made into the injection form of β-asarone.

Embodiment 3

[0025] Take 10g of β-asarone, 5g of Tween, and 90g of sodium chloride, dilute to 1000ml with water, prepare an aqueous solution of β-asarone with a concentration of 10g / L, mix well, put it into a medicine bottle, seal it, and sterilize it. Prepare the oral liquid form of β-asarone.

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Abstract

The invention relates to an application of beta-asarone to the field of drug preparation, in particular to an application of beta-asarone to the preparation of drugs for suppressing liver metastases of colorectal cancer and the like. beta-asarone has the effects of suppressing tumor cell growth and suppressing tumor cell metastases, and is used for treating or preventing the suppressing liver metastases of the colorectal cancer.

Description

technical field [0001] The invention relates to the application of β-asarone in the field of pharmacy, in particular to the application in the preparation of drugs for inhibiting colorectal cancer liver metastasis and the like. β-Asarone has the effect of inhibiting tumor cell growth and tumor cell metastasis, and is used for treating or preventing liver metastasis of colorectal cancer. Background technique [0002] Malignant tumor is one of the common chronic non-communicable diseases in the world. Surgery, chemotherapy, radiotherapy and biological therapy are the common methods to treat tumor patients in medicine. However, some patients have already metastasized when the tumor is found, and they lose the opportunity for surgery. At the same time, due to the dual limitations of equipment and tumor types, the effectiveness of radiotherapy needs to be improved. Biological therapy is an emerging treatment, but it is only effective for some specific tumors, and its safety nee...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/09A61P35/04
CPCA61K31/09
Inventor 周锦勇陈玉根王瑞平
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM
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