Processing method for prepared kusnezoff monkshood roots

Abstract

The invention relates to the field of prepared kusnezoff monkshood roots which are traditional Chinese medicine decoction pieces, in particular to a processing method for prepared kusnezoff monkshood root medicinal materials. The method includes the following steps that a, unprocessed kusnezoff monkshood root medicinal materials are obtained, cleaned with water and then soaked in water, the mass ratio of the medicinal materials to the water is 1:(6-10), and the water is replaced once every 12 hours; b, HPLC detection is carried out on soaking liquid, according to a detection result, soaking can be finished when the total concentration of aconitine, mesaconitine and hypaconitine in the soaking liquid is 10-20 mg / L, the medicinal materials are taken out, placed in a cooking pot and boiled in the way of adding water, the mass ratio of the medicinal materials to the water is 1:(6-10), and clear water is replaced once every an hour; and c, the medicinal materials are boiled for 2-4 hours, then taken out, dried in the air, sliced, and dried for 4-6 h at the temperature of 65-75 DEG C, and processed kusnezoff monkshood root products, namely the prepared kusnezoff monkshood roots can be obtained. By the adoption of the method provided by the invention, kusnezoff monkshood root medicinal materials different in quality can be processed effectively, prepared kusnezoff monkshood root products meeting the national pharmacopeia standard are obtained, and economic benefits of enterprises are increased while vast patients are benefited.

Description

technical field [0001] The invention relates to the field of preparing Aconitum aconitum from decoction pieces of traditional Chinese medicine, in particular to a processing method for preparing Aconitum aconitum medicinal material. Background technique [0002] Aconitum aconitum is the dry tuber root of Aconitum aconitum, a plant of the family Ranunculaceae. It originated from "Shen Nong's Materia Medica", also known as Aconitum aconitum, aliases: five poisonous roots, Aconitum aconitum, heartbroken grass, duck head, Artemisia annua, chicken head grass , Centipeda. Grass Aconitum was known to our ancestors as early as 2000 years ago. It has the functions of expelling wind and dampness, warming meridians and relieving pain. Aconitine is highly toxic, and the main toxic components are diester alkaloids such as aconitine, neoaconitine and hypoaconitine. Adults will produce poisoning reaction after oral administration of 0.2mg, 2~4mg·kg -1 Can cause death. Therefore, the med...

AI Technical Summary

Problems solved by technology

[0008] There is an obvious defect in these methods in the prior art, that is, there is no effective monitoring means in the processing process, so it is impossible to make scientific adjustments to the processing process according to the raw material situation (due to the alkaloid content and variety of Aconitum radix, growth The environment, etc. are closely related and vary greatly, so it is difficult to guarantee the stability of different batches of raw materials. Even if the raw materials are sampled and tested before processing, it is difficult to represent the whole due to sampling limitations), which eventually leads to stable quality of the final product Poor performance, difficult to meet the requirements of the Pharmacopoeia

Images