Linoleic acid and vitamin E capsule and pill two-dimensional rutin tablet, and preparation method thereof

Abstract

The invention discloses a linoleic acid and vitamin E capsule and pill two-dimensional rutin tablet, and a preparation method thereof. The linoleic acid and vitamin E capsule and pill of the linoleic acid and vitamin E capsule and pill two-dimensional rutin tablet includes linoleic acid, vitamin E, glycerin and gelatin according to a weight ratio of (213-225):1:(18-23):(98-105); the two-dimensional rutin tablet comprises auxiliary materials and 12.1-52% of raw materials; the raw materials comprise vitamin C, vitamin B6 and rutin according to a weight ratio of (9.5-10.5):1:(4.95-5.05); and the auxiliary materials include microcrystalline cellulose, pregelatinized starch, aerosil and magnesium stearate according to a weight ratio of (11.7-13.6):(8.0-9.3):(1.2-1.5):1. The raw materials and the auxiliary materials are taken together to treat hypercholesterolemia and atheromatosis, and the linoleic acid and vitamin E capsule and pill two-dimensional rutin tablet has the advantages of uniform capsule and pill thickness, difficulty in destroy, and less adhesion.

Description

technical field [0001] The invention relates to a compound oral solid preparation hypolipidemic drug composed of two dosage forms, in particular to a linoleic acid vitamin E capsule two-dimensional rutin tablet and a preparation method thereof. Background technique [0002] Hypercholesterolemia and atherosclerosis are high incidence cases in the modern population. Hypercholesterolemia means that the cholesterol content in the blood exceeds the normal value, and the normal value is generally 5.7mmol / L. Atherosclerosis is the main cause of coronary heart disease, cerebral infarction, and peripheral vascular disease. Lipid metabolism disorder is the basis of atherosclerosis, which is characterized by the involvement of arterial lesions starting from the intima, usually with accumulation of lipids and complex carbohydrates, hemorrhage and thrombosis, followed by fibrous tissue hyperplasia and calcium deposition, followed by There is gradual degeneration and calcification of th...

AI Technical Summary

Problems solved by technology

[0003] Linoleic acid vitamin E capsules and two-dimensional rutin tablets are suitable for hypercholesterolemia and atherosclerosis. There are still relatively few studies, and no detailed formula and process for reference are given, which limits its development and application